Pre-clinical medicine Books

TRP channels play a key role in sensory physiology and have been the focus of intensive investigation in recent years. The proposed book will be a comprehensive, detailed overview of the ways in which TRP channels are involved in a wide variety of...

This volume contains original submissions on the development and application of molecular imaging computing. The editors invited authors to submit high-quality contributions on a wide range of topics including, but not limited to:• Image Synthesis &...

This comprehensive volume on the blood-gas barrier (BGB) among vertebrates covers its structure and composition along with aspects of evolution, bioengineering, and morphometry. The book also discusses the embryological development of the BGB, including...

This book provides a timely review of the role of histone modifications in epigenetic control of gene expression. Topics covered include: basic mechanisms of molecular recognition of histone post-translational modification (PTMs); combinatorial readout...

The objective of this book is to catalyze the application of genomics to the diagnosis and treatment of oral diseases by comprehensively presenting focused discussions on the current state of knowledge. The first section book provides basic information...

The aim of molecular diagnostics is preferentially to detect a developing disease before any symptoms appear. There has been a significant increase, fueled by technologies from the human genome project, in the availability of nucleic acid sequence...

Intended for readers with a background in fertility medicine as well as those less familiar with IVF, this comprehensive work presents an update on preimplantation genetic testing to enable single embryo transfer (SET). An international cast of...

This book contains an interesting and state-of the art collection of chapters presenting several examples of attempts to developing modern tools utilizing computational intelligence in different real life problems encountered by humans. Reasoning,...

Providing the most up-to-date research and current clinical knowledge of diabetic bone disease and the challenges still facing the research and clinical care communities, this book unites insights from endocrinology and orthopedics to create a truly...

Written for non-experts, this volume introduces the mechanisms that underlie reticulate evolution. Chapters are either accompanied with glossaries that explain new terminology or timelines that position pioneering scholars and their major discoveries in...

Foreword.- Early growth and later health: findings from the Helsinki Birth Cohort Study by Johan G. Eriksson.- Male and female placentas have divergent transcriptomic and epigenomic responses to maternal diets: not just hormones by Anne Gabory, Alexandre...

The Radiology Department is a pivotal part of any acute and/or comprehensive health care facility. The radiologist can no longer just "hide out" there. Matters of imaging are often public concerns, larger in scope than just the scheduling and managing of...

This book presents the state of the art of type 2 diabetes genetics, from the process of genetic discovery to its interpretation and clinical application, and illustrates a model for other complex human phenotypes.The first section explores genome-wide...

The aim of this book is to provide the target audience, specifically students of Medicine, Biology, Systems Biology and Bioinformatics, as well as experienced researchers in research fields relevant to metabolic syndrome (MetS)...

This book provides an introduction to the principles of both cardiovascular epidemiology and molecular pathophysiology; as a unique aspect, it also outlines and discusses the molecular concepts underlying epidemiological...

T. Hara, I. Kimura, D. Inoue, A. Ichimura, and A. Hirasawa: Free fatty acid receptors and their role in regulation of energy metabolism. B. Nilius and G. Appendino. Spices: the savory and healthy science of pungency.

This title discusses all aspects of non-infectious and non-cancer- so called NINC - vaccines. Hypertension, diabetes and allergy vaccine development are referred to as well as the use of adjuvants and nanotechnology in vaccine...

It is well known that estrogen is "somehow" a protective hormone for various age-related disorders. This book provides a solid knowledge of estrogen's neuroprotective activities in the brain with a special emphasis on ...

Schizophrenia has been the subject of intense research interest in recent years, as investigators have explored the biological bases for the disorder and for various approaches to its diagnosis and treatment. This volume...

Functional electrical stimulation is the most important application in the field of clinical treatment with currents or magnetism. This technique artificially generates neural activity in order to overcome lost functions of the...

This book summarizes all new data obtained after development of methods of Golgi complex sub fractionation, molecular biology and microscopy. It collects the full range of expertise, different points of view and different...

In 1992, a group of scientists including molecular biologists, microbiologists, population biolo­ gists, ecologists, human geneticists, moral philosophers and others met discussing the state of affairs regarding the deliberate...

Skeletal muscle consumes significant amounts of oxygen, and its oxygen flux increases significantly under conditions of exercise and muscle contraction. This makes the muscle vulnerable to oxidative stress since concomitantly...

This book provides an account of the recent advances in our understanding of the role of proteases under physiological and pathological conditions. It reviews the contributions that have been made in the fields of biochemistry,...

This volume of Progress in Inflammation Research is a unique compilation of work performed by a wide spectrum of investigators from different medical disciplines. It is fascinating that dietary alterations of fatty acid intake...

Many advances have been made in the field of thermoregulation in the past few years. These include our understanding of Fever, which is now considered not simply a rise in deep body temperature foHowing infection, but just one...

Chronic obstructive pulmonary disease (COPD) ranges amongst the commonest diseases in the world. The relentless progression of the disease causes a pressing need for a better understanding of and therapies for COPD. This volume...

Arachidonic acid (AA) and other 20 or 22-carbon polyunsaturated fatty acids (PUFAs) are precursors of lipid mediators of inflammation known as eicosanoids. These mediators are critical in disease processes and in regulating...

Gene therapy for inflammatory diseases is a new , burgeoning field of medicine. Edited by the undisputed pioneers of this area of research, this volume is the first devoted to its topic. It contains thirteen chapters, each...

18. 2 Principle of FACE/Gel Retardation Assay . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 349 18. 3 Labelling of Oligosaccharides with ANTS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ...

Oxidative stress and aging Over the past several years there has been an extraordinarily rapid growth in our knowledge of free radical chemistry and its possible involvement in both normal essential biology and age­ related...

MicroRNAs as the endogenous mediators of RNA interference have experienced an unprecedented career in recent years, highlighting their pathogenic, diagnostic and potential therapeutic relevance. Beside tissue microRNAs, they are also found in body...

Most studies on autonomic innervation of smooth muscle have focused on the short-term mechanisms involved in neurotransmission in physiological and pathophysiological conditions. However recent obser­ vations of the long-term...

This volume arose from the scientific program of the XIIth International Congress of Pharmacology, held in Montreal, Canada, July 24-29, 1994. The scientific program included plenary lectures and symposia, in addition to poster...

Medical research involving human subjects has contributed to considerable advancements in our knowledge, and to medical benefits. At the same time the development of new technologies as well as further globalisation of medical research raises questions...

The Mongolian gerbil brain lies in the anatomy of the blood vessels supplying blood to the brain. In all mammals, there is a special mechanism that compensates for the decreased blood flow to the brain in the case of development of stroke. This mechanism...

This book provides the most valuable and updated research on computational and mathematical models in biological systems from influential researchers around the world and contributes to the development of future research guidelines in this topic.Topics...

This book contains subjects by authors with a fresh, exciting and extensive focus within the medical humanities, offering the reader chapters which include the history of medical illustration, Graphic Medicine as a vehicle for the expression of...

This book discusses modelling and analysis of Magnetic Resonance Imaging (MRI) data of the human brain. For the data processing pipelines we rely on R, the software environment for statistical computing and graphics. The book is intended for readers from...

Muscle is the only tissue of the four basic types that make the body that can be completely ablated while allowing fetal survival. This book is a result of 25 years of research employing engineered mouse fetuses with no skeletal muscle, a model system...

This book aims to promote the interaction among the scientific community to discuss applications of CS/AI with an interdisciplinary character, exploring the interactions between sub-areas of CS/AI, bioinformatics, chemoinformatics, and systems biology...