Thisvolume focuses on the roles of long non-coding RNAs (lncRNAs) in contextsranging from human cancers to cardiovascular disease and ageing. The role oflncRNAs in X-inactivation and those lncRNAs derived from pseudogenes, pastretroelements integrated within the human genome, as well as the role thesepseudogene-derived lncRNAs play in cancer development are discussed in detail. Further,the book examines the function of lncRNAs in diseases such as diabetes, in smoothmuscle formation, and in the modulation of nuclear receptors, as well as inconnection with perspectiveson the development ofpersonalized therapeutics. It offers an appealing and insightful resource forscientists and clinicians alike.
Thisvolume focuses on the roles of long non-coding RNAs (lncRNAs) in contextsranging from human cancers to cardiovascular disease and ageing. The role oflncRNAs in X-inactivation and those lncRNAs derived from pseudogenes, pastretroelements integrated within the human genome, as well as the role thesepseudogene-derived lncRNAs play in cancer development are discussed in detail. Further,the book examines the function of lncRNAs in diseases such as diabetes, in smoothmuscle formation, and in the modulation of nuclear receptors, as well as inconnection with perspectiveson the development ofpersonalized therapeutics. It offers an appealing and insightful resource forscientists and clinicians alike.
This second edition provides a broad spectrum of methods used in long non-coding RNAs (lncRNA) research, ranging from computational annotation of lncRNA genes to molecular and cellular analyses of...
This volume presents techniques needed for the study of long non-coding RNAs (lncRNAs) in cancer from their identification to functional characterization. Chapters guide readers through...
Preface.- Chromatin regulation by long non-coding RNAs.- Regulation of Eukaryotic Cell Differentiation by Long Noncoding RNAs.- Roles of long non-coding RNAs in X-chromosome inactivation.- Roles of...
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