Pre-clinical medicine Books

This well-baby book teaches how to prevent infections, manage common infant minor emergencies, and may save you a trip to the ER. It covers all the common illnesses that affect babies & young children, including summer stomach flu, vomiting,...

  

This book explores the major cytokines, such as IL-1 and IFN-γ, with respect to the regulation of their gene expression and protein production in specific immune cell types. It discusses both healthy physiological settings and in pathological situations...

This volume is a reference handbook focusing on diseases like Marfan syndrome, Ehlers-Danlos syndrome, Loeys-Dietz syndrome and other heritable soft connective tissue diseases. The book presents detailed information for both basic scientists and for...

ß-barrel outer membrane channel proteins (OMP) are useful as robust and flexible models or components in nanotechnology. Over the last decade biotechnological techniques allowed to expand the natural characteristics of OMPs by modifying their geometry...

Cellular and Molecular Control of Neuronal Migration provides an up-to-date collection of reviews on the molecular and cellular principles of neuronal migration in the mammalian brain. Over the last decades a rich catalogue of signaling molecules...

G protein-coupled receptors (GPCRs) are heptahelical transmembrane receptors that convert extra-cellular stimuli into intra-cellular signaling, and ultimately into biological responses. Since GPCRs are natural targets for approximately 40% of all modern...

The study of carbonic anhydrase has spanned multiple generations of scientists. Carbonic anhydrase was first discovered in 1932 by Meldrum and Roughton. Inhibition by sulfanilamide was shown in 1940 by Mann and Keilin. Even Hans Krebs contributed to...

This book is the product of a unique collaboration by experts from leading international, regional and national agencies and professional organizations discussing on the current 'hot' issue on the judicious use and safety of radiation in radiology. There...

This edited reflects the current state of knowledge about the role of microRNAs in the formation and progression of solid tumours. The main focus lies on computational methods and applications, together with cutting edge experimental techniques that are...

Color perception plays an important role in object recognition and scene understanding both for humans and intelligent vision systems. Recent advances in digital color imaging and computer hardware technology have led to an explosion in the use of color...

Handbook of Capsule Endoscopy is a concise guide to the clinical diagnostic use of capsule endoscopy, a non-invasive imaging technology of the gastrointestinal tract. This book is written by an international team with over 30...

Traditional research methodologies in the human respiratory system have always been challenging due to their invasive nature. Recent advances in medical imaging and computational fluid dynamics (CFD) have accelerated this research. This book compiles and...

Computational neurosciences and systems biology are among the main domains of life science research where mathematical modeling made a difference. This book introduces the many different types of computational studies one can develop to study neuronal...

The phrase "Life, stress and death" connects three terms, but is there a biological basis for that? Are there molecules that are essential to/or mediate these phenomena? This contributory volume "Mortalin Biology: Life, Stress and Death" is a remarkable...

This work presents the most advanced discoveries from translational research laboratories directly involved in identifying molecules and signalling pathways that play an instrumental role in metastasis. In contrast to other works, conventionally focused...

Phosphoinositides play a major role in cellular signaling and membrane organization. During the last three decades we have learned that enzymes turning over phosphoinositides control vital physiological processes and are involved in the initiation and...

The post-genomic era has brought new challenges and opportunities in all fields of the biology. In this context, several genome engineering technologies have emerged that will help deciphering genes function by as well as improve gene therapy strategies...

"Applied Computational Genomics" focuses on an in-depth review of statistical development and application in the area of human genomics including candidate gene mapping, linkage analysis, population-based, genome-wide association, exon sequencing and...

Thisbook provides readers an extensive overview of recent progress in basicand clinical research on cancer immunotherapy. Thanks to rapid advances inmolecular biology and immunology, it has become increasingly evident thatcancer growth is influenced...

The Molecular Biology ofChloroplasts and a genetic dissection ofphotosynthesis was first Mitochondria in Chlamydomonas is the seventh recognized by Paul Levine. Together with his volume to be published in the series Advances in...

A shortage of water exists, not only in the arid regions of the world, but even in some moderately humid climates. This situation is a consequence of water require­ ments for agriculture and industry in amounts greater than the...

Throughout its history, medicine has benefited from scientific discov­ eries made in complementary fields such as chemistry, physics and biology. Thus, in the middle of the last century, the works of Pasteur, a chemist and...

The present volume "Excitation Energy and Electron Transfer in Pho· tosynthesis" is dedicated to a colleague and dear friend Warren L. But­ ler. I first met Warren when he visited the University of Illinois at Ur­ bana during...

The series of workshops sponsored by the European Communities started with "Methodology of PET" at Hammersmith Hospital, London, in March 1984. This was followed by "Radiochemistry, Methodology and Standardization in PET" at...

The basic mechanism underlying directional differences in excitability, con­ duction velocity, andsafetyfactor thatleadtocircusmovementreentry incardiac muscle is generally attributed to a spatial difference in the refractory...

List of Contributors ix PART 1 CURRENT CONCEPTS OF HEALTH AND HEALTH CARE 1 A European overview of the health care scene KS Johansen 3 Is there a European concept of health and health care? 2 JGW Wittkiimper 7 3 The effects of...

Since the discovery of LHRH in 1971, research into the physiology and therapeutics of this compound can be divided into three dis­ tinctly different phases. In the first phase, attention was paid chiefly to the natural sequence...

Infertility is a problem for the couple and evaluation of the couple is preferable in a clinic where both males and females may be seen together. The contribution to care by the urologist and the gynaecologist each with an...

This monograph represents an attempt to collect the methods developed within the past decade in which echocardiography was being used to guide or to assess the results of some cardiovascular interventions or to overcome the...

It is hoped that this book may serve two purposes. felt that the resulting increase in size and expense of First it is intended for use at the bench. to help solve the book would not be justified. some of the problems of cell...