Pre-clinical medicine Books

As I reflect on the evolution of this book, I am struck by the differences be­ tween my early conceptions and the final product. When I was first ap­ proached by Springer-Verlag regarding a monograph on my interests in the area...

This monograph brings together our work concerning the relationships be­ tween the hypothalamus, pituitary and testis. The studies span approximate­ ly a decade of collaborative work. Over this period our contributions and...

Dr. Raymond Pederson, Dr. Jill Dryburgh and I commenced work on GIP in 1968, when, with the generous help of Professor Viktor Mutt and Professor Erik Jorpes of the Karolinska Inst,itute, Stockholm, we were able to establish...

Die generalisierten Osteopathien sind Systemerkrankungen des Skelettes, deren Patho­ genese sehr unterschiedlich sein kann. Das pathogenetische Spektrum beginnt mit den angeborenen Enzymdefekten bei den Dysostosen, die fUr den...

This book has been conceived as a reference for all those who want to deepen their knowledge of technical details, design concept and interac­ tion of the individual modules of Zeiss operation microscopes. The sub­ jects of the...

The present monograph will concern itself with those disorders of the endocrine system, either associated with destruction, interference with function or hyper­ function, which are considered to be due to auto-immune processes...

When I was asked by the late Professor Wolfgang Bargmann in 1973 to write the continuation of his review article on the epiphysis cerebri published in the present Handbuch Series in 1943 I felt greatly flattered and readily...

The cytochemical bioassay system was described in a short abstract in 1971, and more fully, in the cytochemical bioassay of corticotrophin, in 1972. Since then, cytochemical bioassays have been described for several polypeptide...

The building of conceptual models is an inherent part of our interaction with the world, and the foundation of scientific investigation. Scientists often perform the processes of modelling subconsciously, unaware of the scope...

The physiology and metabolism of thyroid hormones were areas of intense research investigation during the 1970s. Radioimmunoassays were applied to study the concentration of iodothyronines in biologic fluids. These techniques...

Research on the hormonal control oflactation - the subject of this monograph - has long been the major interest of this laboratory. Studies were initiated in the mid 1930s by the late Professor S. 1. Folley, FRS, who directed...

Upon wresting the control of the earth from the Titans, Zeus assigned the task of creating living creatures to two Titan brothers who had sided with him in the epic battle just concluded. Because Epimetheus, who had been...

The purpose of this monograph is to describe theoretical aspects of the interpretation of data obtained from experiments performed with labeled hormones. Quantitative endocrinologic studies involving the use of tracers include...

With contributions by numerous experts

This book was written at the invitation of Dr. H. GOTZE of Springer-Verlag for the series "Monographs in Endocrinology". It is not a comprehensive account of the prostaglandins but has been writ­ ten with a deliberate emphasis...

Clinical trials with Lipiodol l3ll were started in 1961 by my associate, S. CHIAPPA, and a group of physicians at the Institute of Radiology and the National Cancer Institute in Milan and development has been vigorously pursued...

"Dost thou love life? Then do not squander time, for that's the stuff life is made oj': Benjamin Franklin This book describes the technical principles and applications of echo-planar imaging (EPI) which, as much as any other...

The diagnosis of osteoporosis and the determination of fracture risk has always been a challenge for radiologists, epidemiologists, and clinicians as well as oth­ er researchers and health care professionals working in the...

The imaging potential of the MR experiment continues to evolve. In recent years, an increasing number of fast and ultrafast imaging strategies has been described. In this evolu­ tion the definition of the terms fast and...

Since the endothelium plays such an important role in the pathophysiology of the circulatory system, the readers attention is directed here towards the possible involvement of these polypeptides in the aetiology of ischaemic...

Biological effects of magnetic fields have been studied in many animals and plants. The magnetic fields were of a wide intensity range and, as alternating fields, of a wide frequency range and of a variety of impulse shapes...

Comparative endocrinology helps to find the roots of homeostatic regulation in organisms. In this context, many years ago a series of experiments were done, which demonstrated the hormonal regula­ tion also on the invertebrate...

Invertebrate animals represent a diversity of solutions to life's challenges. Success in a wide range of environments has been achieved by an almost bewildering range of invertebrate body forms. These body forms are reflected...

In nearly all areas of technology our generation is experiencing the phenomena of fast paced innovation and great bursts in development. Besides the completely new techniques, the "experienced user" is astonished when obviously...

A comprehensive and systematic survey of the present knowledge of the structure and physiological functions of smooth muscle and its response to endogenous substances and pharmacological agents. The latter includes findings on...

A compilation of researchers' experience in the areas of bioanalysis, pharmacokinetics, and drug metabolism, to present an up-to-date and comprehensive treatise on the application of these and related technologies in drug...

Mitochondrial transport systems are essential to mitochondrial function and therefore to energy homeostasis within the cell. The book contains studies utilizing the techniques of biochemistry, physiology, molecular biology and...

Atherosclerosis still affects over 50 % of the population in the highly industrialized countries. This book is an update of the treatment of hyperlipidemia, necessary due to the identification in recent years of molecular...

The past 15 years have witnessed a marked increase in attempts to identify safe and effective treatment alternatives to prostatectomy. This book is a review of the current therapeutic efforts in the management of patients with...

The purpose of this book is to provide some basic information regarding the fundamentals of magnetic resonance (MR) for all those who are less familiar with the technique and interested in MR spectroscopy and its possible...

The various congresses on growth hormone (GH) which have been held in Milan since 1967, the Milan Congresses, have witnessed over 25 years the tremendous expansion of a research field that was based initially upon the scarce...

The authors, all accomplished and world-renowned experts in their topic areas, have provided controversial and up-to-date accounts of the current status of research in calcium and bone metabolism by reviewing major areas of...

Liver surgery has made extraordinary progress over the past 40 years, evolving from the first, timid partial resections in the 1950s to today's major resections and organ transplants. Examining the rea­ sons for this progress,...

Since the thalidomide (Contergan) tragedy about 30 years ago the induction of prenatally-induced morphological or functional defects has been an area of extensive research. Risk assessment of prenatally-induced adverse health...

There has long been disagreement about various aspects of the structure and function of the "gatekeeper" (Greek pyloros, from pyle = gate and ouros = guard). In recent years the problem has often been mentioned in anatomy,...