Pharmacology Books

The appreciation of risk like the awareness of beauty lies very much in the eyes of the beholder. It involves a value judgement and can never be absolute. Yet paradoxically, modern society is demanding ever greater degrees of...

The third CMR Workshop prov. ided the opportunity for a group of experts from the Industry, academia and the regulatory authorities to meet and discuss ways and means by which risk benefit decisions are made during the various...

High blood pressure (BP) (with fats and smoking) is one of the three roots of cardio-cerebro-renovascular disease affecting up to 25% of the adult population. Hence, high blood pressure should be recognized and treated, to...

. Aggression research is in a rapid state of development. The accelerating knowledge of neurotransmitter systems in the brain, their behavioural functions and the development of drugs which may specifically affect systems...

Reproduction and fetal development in humans and experimental animals may be adversely affected by a wide range of drugs and environmental agents. They may be toxic in the parental generation leading to impaired germ cell...

The original series, Advances in Prostaglandin Research, edited by Sultan M. M. Karim, was published by MTP Press in three volumes in 1975 and 1976. A glance at those books illustrates the progress that has been made since then...

At present we may be at the cross-roads in the therapeutic approaches we have for the treatment of the 100 or more rheumatic conditions. This is be­ cause we now recognise that although some advances have been made with the...

As 1992 looms on the horizon and preparation is made for the completion of the internal market in Europe, the CMR realised the value of addressing some of the issues involved and defining the objectives and achievements of...

Azapropazone is a chemically unique non-steroidal anti-inflammatory drug (benzotriazine oxide) which has found successful clinical applications in the therapy of a wide variety of arthritic conditions. This book summarizes the...

Many of the most effective treatments for disease have been discovered empir­ ically. Nowadays, however, we think that understanding the biology of a disease will lead us to design better treatments, and to improve the...

Most of the anti-cancer drugs in use today were discovered by happy accident rather than design, yet the rational design of better anti-cancer drugs remains a cherished goal, and one of the most important challenges facing...

Jurgen Schulte and Christian Endler met in 1990 at an international conference on the Structure of Water held in the Lecture Halls of the University of Graz (Austria). Disappointed by the lack of a systematic strategy of...

In the two decades since the elusive "slow reacting substance of anaphylaxis" (SRS-A) was identified as a product of the action of the 5-lipoxygenase enzyme on arachidonic acid, it has been well established that the ...

The availability of analgesics and non-steroidal anti-inflammatory drugs (NSAIDs) sold over-the-counter (OTC) to the public without prescription has become an issue of major concern in recent years. The problem has been...

ACE inhibitors are one of the most exciting and interesting of recent medical developments. They fit the patho-physiologica1 processes of cardiovascular disease with fascinating precision and are a constant stimulus to the...

The metabolic N-oxidation ofnitrogenousxenobiotics has been reported tc occur in many biologicalsystems, in addition to mammaliantissues, and the mechanisms appear to differ in many respects from those involved in oxidative...

The desirability of quality-assay of ingestable or imbibable material has resulted in an established procedure in advanced countries. Testimony to its necessity was borne by the scandal of chateau-bottled Bordeaux crus classes...

Clinical research represents an integration of many procedures from the social, biological, and natural sciences. Critical examination of the spectrum of medical inquiries will reveal the full gamut of research activities...

Ever since the industrial revolution, large numbers of environmentally hazardous materials are in­ troduced into the global environment annually; a list of all substances which are at present re­ garded as environmentally...

The rapid development in the knowledge about the synthesis and metabolism of the various products derived from arachidonic acid is a continuous chal­ lenge for those who intend to measure these substances in biological fluids...

The publication of this volume, which is based upon presentations made to the Third European Symposium on Radiopharmacology at Noordwijkerhout, April 22 - 24, 1982, is indicative of the continued interest in this sub-branch of...

1.1 Organisation and aims This International Seminar, organised jointly by the Com­ mission of the European Communities and the United States authorities (Occupational Safety and Health Administration and the National Institute...

Ever since Rachel Carson's Silent Spring, we have generally become aware of environmental contaminants and their effects on the ecosystem. The findin~ of PCB's in fish by Soren Jensen in Sweden, the recognition of mirex as...

This volume focuses exclusively on those endocytic processes that sequester proteins by a selective, receptor-mediated mechanism. In such an endocytic process, cell surface receptors specifically bind protein ligands and...

This book would combine chapters written by the most qualified authors around the world whose research encompasses the effect of morphine or other opioids on tumor growth and metastasis. This includes clinicians involved in trials determining which type...

Drug-related problems in the elderly is intended to serve as a source of information and clinical support in geriatric pharmacotherapy for students as well as all health care professionals, e.g. physicians, nurses and pharmacists. Pharmacotherapy is of...

This book features a special subsection of Nanomedicine, an application of nanotech­nology to achieve breakthroughs in healthcare. It exploits the improved and often novel physical, chemical and biological properties of...

Engineered antibodies currently represent over 30% of biopharmaceuticals in clinical trials and their total worldwide sales continue to increase significantly. The importance of antibody applications is reflected in their...

Therapeutic regimens for visceral leishmaniasis (also Kala-azar, Dum-dum fever or black fever), caused by parasitic protozoa of the Leishmania genus, evolve at a pace never seen before. Spread by tiny and abundant sand flies,...

Turkish and Other Baths: A Guide to Good Health and Longevity, is a classical book and has been considered important throughout the human history. So that this book is never forgotten we at Alpha Editions have made efforts in its preservation by...

This volume presents research on current trends in chemical regulations - a fa- growing, complex, and increasingly internationalized field. The book grew out from a multidisciplinary research project entitled 'Regulating...

"Apoptosome" is the first book that presents a concise synthesis of recent developments in the understanding of how the activation of the cell death cascade is handled by a cytosolic signalling platform known as the apoptosome...

clinical efficacy of haemostatic agents had to be published work and had to fulftl most of the following minimum requirements: (1) Quantitation ofthe measured blood loss was required, and not merely a clinical impression of the...

Rabies is the deadliest zoonotic disease that threatens humans and animals on all continents except Antarctica. Asia and Africa are worst affected as more than 95 per cent of rabies associated human deaths occur in these regions. India alone bears about...

 The book aims to cover basic physiologic functions of melatonin, and its therapeutic applications in humans for a variety of clinically relevant disorders. This book contains chapters on the recent aspects of melatonin...

On the threshold of an exciting new era for acute stroke diagnosis and treatment, the Third International Symposium on Thrombolytic Therapy in Acute Ischemic Stroke was held in Nara, Japan, in April 1994. The symposium brought...

In this volume, which is based on the proceedings of the international symposium "Functional Linkages Between the Cerebral Cortex and Basal Ganglia in the Control of Voluntary Movement", held December 1993 in Osaka, Japan, the...

How to protect against ischemia/reperfusion damage is one of the most urgent problems in medicine. It is known that ischemic damage can be attenuated by improving the oxygen balance of the ischemic heart, but the ...

Research centering on blood flow in the heart continues to hold an important position, especially since a better understanding of the subject may help reduce the incidence of coronary arterial disease and heart attacks. This...

Recent research has given great insight into the physiological and pharmaceutical effects of histamine on the central nervous system and especially on the brain. This volume focuses on these many new findings, including the...

The Second Meeting of the International Society for Trace Element Research in Humans (ISTERH) was held in Tokyo from August 28 through September 1,1989. On August 27, the day preceding the opening of the meeting, a typhoon made...

Ascidians are the invertebrate group that gave rise to vertebrates, thus the biology of ascidians provides an essential key to understanding both invertebrates and vertebrates. This book is the first to cover all areas of...

At the Fifth International Neuromuscular Meeting held in Tokyo in 1994, leading experts in the field came together to discuss the physiology and pharmacology of neuromuscular receptor sites and neuromuscular blocking agents...

At the Mie International Symposium held in Japan in April 1994, leading scientists reviewed recent advances in the understanding of the contractile mechanism in smooth muscle. The present volume collects the papers presented at...