Pharmacology Books

The Analog Potential in Cancer Chemotherapy in the United States and Japan S. K. Carter Northern California Cancer Program, 1801 Page Mill Road, Building B, Suite 200, USA - Palo Alto, CA 94304 The bilateral collaborative...

Since cytotoxic drugs were first developed, their damaging effects on bone marrow have attracted considerable interest. We now know that the bone marrow is an organ with rapid cell renewal in which maintenance of the ...

During the last decade physical and chemical methods have improved rapidly - a fact which allowed the mode of action of antibiotics to be studied - and many biochemically-oriented scientists have devoted their research to the...

Acamprosate is the first new anticraving agent used prophylactically to prevent relapse in alcohol-dependent patients. This book presents an overview on basic mechanisms in alcohol dependence and craving and all the preclinical...

In the first of three sections of this book, an overview of in vitro toxicology is provided. The molecular biology of cellular toxicity, receptor-mediated mechanisms, structure-activity relationships, pharmacokinetic modeling,...

Since the endothelium plays such an important role in the pathophysiology of the circulatory system, the readers attention is directed here towards the possible involvement of these polypeptides in the aetiology of ischaemic...

This book records the presentations given at a workshop held in Bonn in May 1994. The aim of the meeting was to bring together scientists from various disciplines and clinicians to discuss within a group of experts the...

Presented here are recent advances in biochemical, toxicological, and regulatory aspects of oxidative drug metabolizing enzymes. Mainly cytochrome P450-dependent and flavin-containing monooxygenases (FMO) are covered. Moreover,...

In any movement of their life, immune cells, especially T and B lymphocytes, are confronted with an essential choice: to continue their existence or to commit a sort of metabolic suicide that is referred to as apoptosis or...

The action of diuretics including cellular mechanisms of action, pharmacokinetics, and clinical usage, with much emphasis placed on the most recent findings on the pharmacodynamics of the respective drugs. During the past...

An insight into new advances of current interest in metal toxicology, such as mechanisms important in risk-assessment for human health. The book also has chapters on emerging conceptual problems including resistance to metal...

A comprehensive and systematic survey of the present knowledge of the structure and physiological functions of smooth muscle and its response to endogenous substances and pharmacological agents. The latter includes findings on...

A compilation of researchers' experience in the areas of bioanalysis, pharmacokinetics, and drug metabolism, to present an up-to-date and comprehensive treatise on the application of these and related technologies in drug...

M. Pliftski Institute of Oceanography, GdaJisk University 46 Pilsudskiego Av. 81-378 Gdynia, Poland 2 The Baltic Sea with 366,000 km is only 0. 1% of the world's oceans but nevertheless, unique in many ways. The Baltic Sea is...

The subject of the book is the pharmacology of ethanol. It brings together the work of both basic and clinical investigators in the pharmacology of alcohol and alcohol abuse. The major focus is on the integration of findings...

Atherosclerosis still affects over 50 % of the population in the highly industrialized countries. This book is an update of the treatment of hyperlipidemia, necessary due to the identification in recent years of molecular...

The GTPase switch appears to be almost as old as life itself, and nature has adapted it to a variety of purposes. This two-volume work surveys the major classes of GTPases, including their role in ensuring accuracy during...

The 1st Euchem Symposium on the Chemical Synthesis of Antibiotics was held in Aussois in Savoie, France on May 2-6, 1988 thanks to the efforts of Prof. G. Lukacs, chairperson, and Prof. F. Arcamone and Prof. P. Welzel,...

A sample of the most exciting developments in the cloning, manipulation, expression and application of genetically-engineered monoclonal antibodies. This rapidly-evolving field has witnessed the PCR combinatorial cloning of...

In-depth coverage of advances in molecular biology, indicating the importance of drug and xenobiotic conjugates as transport forms of biologically active compounds. Part One describes molecular events associated with the...

This monograph summarizes the results of the authors' own in­ vestigations as well as relevant literature data about the mechanism of synaptic transmission in sensory hair cells of the acousticolater­ al system. It deals mainly...

In this volume the impact of cell culture models on dermatological research is discussed by scientists from medicine, physiology, biology, pharmacology,and pharmacy. The book includes the following topics: orthology and...

Since the thalidomide (Contergan) tragedy about 30 years ago the induction of prenatally-induced morphological or functional defects has been an area of extensive research. Risk assessment of prenatally-induced adverse health...

This two-volume book provides the first comprehensive survey of opioid research, a field which has accumulated a tremendous amount of literature since the identification of opioid receptors and their endogenous ligands. In more...

The most comprehensive and conceptual one-volume treatment of this field available and the first to emphasize the cellular and molecular aspects of gut peptide biology. Authored by an array of internationally distinguished...

Im h|heren Lebensalter nimmt die Zahl der Erkrankungen zu. Oft m}ssen mehrere Medikamente gleichzeitig eingesetzt werden. Durch die altersbedingten Organver{nderungen wird jedoch die Wirkung der Medikamente ...

This two-volume book provides the first comprehensive survey of opioid research, a field which has accumulated a tremendous amount of literature since the identification of opioid receptors and their endogenous ligands. In more...

Studies on the colon not only serve medical interest or clinical purposes, but are also a highly interesting subject of comparative physiology, from which we can learn much about the basic principles in physiology. Presented...

I am honored to be invited to prepare a foreword for the proceedings of the Second International Lubeck Conference on Erythropoietin (Epo). I congratulate Wolfgang Jelkmann, Horst Pagel and Christoph Weiss for their ...

during the past few years increasing interest has been focused on the role of gamma-aminobutyric acid (GABA) outside the central nervous systems (CNS).Biochemical, pharmacological, histochemical, physiological approaches have...

The blood-brain barrier is still not completely understood and therefore the subject of fascinating study. How are endogenous substances transported through the blood-brain barrier? What are the known therapeutic and toxic...

Dermatology is a complex and puzzling world of itching bumps, pim­ ples, and rashes. The multitude of clinically distinct skin diseases, their frequently unresolved pathogenesis, and the exponentially in­ creasing amount of...

In this book the pathophysiology, diagnosis, and therapy of most aspects of peptic ulcer disease are examined in detail. Covered are the pharmacology of the parietal cell and the latest hypotheses for the development of...

This volume forms part of a prestigious series and covers the latest advances in our understanding of the pathophysiology and treatment of asthma. Our understanding of asthma has changed dramatically in recent years, and much...

A large number of chemical agents are known which affect blood and blood-forming organs. The purpose of this volume is to review the sig­ nificant advances made over the past several years regarding such chemical agents. The...

Together with the two previous volumes of the Handbook of Experimental Pharmacology on histamine and antihistamines the present publication yields a picture of a still rapidly developing field of research. New techniques and...

Louis Lewin war als Toxikologe und Autor mehrerer weltweit verbreiteter Fachbiicher eine markante Gelehrtenpersonlichkeit des Berliner Geisteslebens im ausgehenden 19. und im ersten Viertel des 20. Jahrhunderts. Sein ...

The use of antibiotics in the treatment by antibacterial and antifungal chemo­ therapy, has become standard practice since the end of World War Two and has had an enormous impact on healthcare throughout the world. Compounds...