Immunology Books

Rapid progress in molecular biology, genetic engineering, and basic research in immunology has opened up new possibilities for application to diagnostic procedures and to clinical research. In a short period a new era of...

Proceedings of the NATO Advanced Study Institute on Immunotoxicology held at Acadia University, Wolfville, Nova Scotia, Canada, 14-23 July 1982

If tumor viruses did not exist in nature they might have been created by scientists interested in basic mechanisms of develop­ ment, differentiation, and tumorigenesis. In contemporary euka­ ryotic cell biology tumor viruses...

For more than ten years cell fusion techniques have been applied in studies on various lymphocyte functions. Ig expression was first studied in hybrids obtained by fusing myeloma cells with fibroblasts (1) or lymphomas (2),...

All but one* of the following articles represent comprehensive reports on a workshop held between 7 and 9 May 1981 at the Institute of Virology and Immunobiology, University of Wfuzburg, Federal Republic of Germany. The title...

Natural resistance is now coming to be recognized as a potentially important phenomenon in host defense against infection and ma­ lignancy. Genetically controlled resistance mechanisms are usUally effective early in infection...

It is with great pleasure and ,much interest that I accepted to write the foreword to this book by Paul Doury, Yves Dirheimer, and Serge Pattin on the subject of "algodystrophy." First, because I know the extent of their...

This volume is not intended as review of the large literature on tumor antigenicity and efforts at tumor immunotherapy. Its pur­ pose, rather, is to present discursively an outline of the likely approaches to immunological...

Haemocyanin was first recognised as a respiratory pigment by P. Bert in 1867. Over the years the haemocyanins have attracted attention as macromolecules and copper-contain­ ing respiratory proteins. The early functional studies...

With the introduction of antibiotics acute inflammatory disease has ceased to be the dominant problem in general medical practice and its place is now increasingly occupied by chronic inflamma­ tory disease of which the...

It was an extraordinary pleasure for me, as the secretary general, to organise, with my collaborators, this Second International Symposium on Antibiotic Resistance in the Castle of Smolenice in Czechoslovakia. We all ...

Prominent progress in molecular biology was only made when it became possible to separate functionally distinct molecules by taking advantage of their biophysical properties. Likewise, the analysis of the functions of hetero­...

This volume contains papers presented at a symposium on "The Role of Lympho­ cytes and Macrophages in the Immunological Response" at the XIII International Congress of Haematology, Munich, August 1970. This symposium was...

A considerable amount of information has been gathered in the field of immunoneurology over recent years. This knowledge about modifications in the pathways of neuroimmune diseases has enabled the development of new therapies...

In metastasis, tumor cells disseminate from the primary lesion and home to secondary organs where they may remain dormant for a long time. Metastasis formation is still the most feared manifestation for tumor patients and...

Renal transport and xenobiotic metabolism play an important role in the detoxication and excretion of potentially toxic xenobiotics. However, recent experimental evidence has demonstrated that renal xenobiotic metabolism and...

This is now the fourth time that protein phosphorylation has been the focus of a NATO Advanced Study Institute. The first meeting with the topic "Signal Trans­ duction and Protein Phosphorylation" was held on the island of...

Pain is a symptom of many clinical disorders, afflicts a large proportion of the population and is largely treated by pharmacological means. However, the two main classes of drugs used are the opioids and the non-steroidal...

Recent progress in the fields of pharmacology and immunology has provided us with new possibilities for treating dermatological diseases. This book reviews the most important immunosuppressive and immunostimulatory drugs and...

The 11 th meeting in "Modern Trends in Human Leukemia" took place from June 19 to 21, 1994 in Wilsede in the middle of the Liineburger Heide, South of Hamburg. Interwoven with the Leukemia program was the Nato-sponsored...

During the last 5 years, major advances have been made in our understanding of the pathogenesis of human immunodeficiency virus (HIV) disease and in the development of new potent antiviral agents. With regard to HIV ...

Discrimination of self from nonself is the major function of the immune system and understanding the mechanism(s) involved a main employer of immunologists. Hence, the age-old puzzle of why a fetus that contains a panel of...

Regulation of gene expression at the level of transcription is one of the major determinants of proper cellular proliferation and differentiation. The key players in these processes are sequence-specific DNA binding ...

There is no doubt among experts that the prevalence of allergic diseases has increased in many industrialized countries in recent years. The rea­ sons for this increase are unknown; only suppositions exist. Many people focus on...

The essence of combinatorial chemistry or techniques involving "molecular diversity" is to generate enormous populations of molecules and to exploit appropriate screening techniques to isolate active components contained in...

This is a pioneering work on the emerging field of artificial immune systems-highly distributed systems based on the principles of the natural system. Like artificial neural networks, artificial immune systems can learn new...

This book is a comprehensive survey of new and exciting developments regarding the role of DNA methylation in human cancer. Issues related to the mutagenicity of 5-methylcytosine and the increase in the interaction of chemical...

This volume provides a review of current research in the field of B cell development and differentiation with particular emphasis on signal transduction processes. The volume is divided into two parts that focus, respectively,...

Zoologists have categorized primates into a single order, and no one doubts today that they share a common ancestry. Humans and Old and New World non­ human primate species, from the lemurs of Madagascar to the African anthro­...

From the first detailed clinical description of the disease in the Midwestern United States in 1918, to the isolation of the causative agent, the first of any influenza virus, in 1930 to its role in the genesis of the 2009 human pandemic, swine have...

This volume is focused on the development of vaccines which generate immune effectors capable of blocking mucosal entry or peripheral pathogen spread. A critical first step in the design of mucosal vaccines is the selection of administration route. Not...

Controversy still exists regarding how early disease-modifying agents (DMA) should be commenced and whether all patients with relapsing-remitting MS should in fact be treated. To answer these questions, it is also important to know the natural history of...

Streptococci are Gram-positive bacteria that cause a wide spectrum of diseases, such as pharyngitis, necrotizing fasciitis and streptococcal toxic shock syndrome, as well as rheumatic fever and rheumatic heart disease as sequelae. Antibiotics alone have...

Notch signaling regulates many cell fate decision and differentiation processes during embryonic development and tissue homeostasis. Moreover, disregulation of the pathway is associated with human disorders and cancer. In the last 15 years it became...

This comprehensive, interdisciplinary book covers different aspects of relevant human pathogens and commensals. The ongoing development of (meta-)genomic, transcriptomic, proteomic and bioinformatic analyses of pathogenic and commensal microorganisms and...

Recent research has focused attention on the importance of intrinsic antiviral immunity, i.e. immunity mediated by factors that are constitutively expressed in many cells. In this volume, leading experts provide a comprehensive overview of this...