Immunology Books

Why sex mattersAmong human and nonhuman animals, the prevalence and intensity of infection typically is higher in males than females and may reflect differences in exposure as well as susceptibility to pathogens. Elevated immunity among females is a...

Gene Regulatory Networks Orchestrating B Cell Fate Specification, Commitment, and Differentiation.- Helix-Loop-Helix Proteins in Lymphocyte Lineage Determination.- Ikaros-Family Proteins: In Search of Molecular Functions During Lymphocyte Development.-...

Malaria is still a major global health problem, killing more than 1 million people every year. Almost all of these deaths are caused by Plasmodium falciparum, one of the four species of malaria parasites infecting humans. This high burden of mortality...

Molecular Mimicry, Microbial Infection and Autoimmune Disease: Evolution of the Concept.- A Virus-Induced Molecular Mimicry Model of Multiple Sclerosis.- Suppression of Autoimmunity via Microbial Mimics of Altered Peptide Ligands.- Molecular and Cellular...

Cytokines and cytokine receptors remain an area of great interest for the development of targeted therapies for cutaneous inflammatory diseases. Anti-TNF therapeutics have proven to be effective in the treatment of psoriasis, and clinical investigations...

Peste de Petits Ruminants (PPR) is a highly contagious viral disease of domestic and wild small ruminants that can significantly affect economies. The authors are experts in the field and provide an up-to-date and comprehensive review covering all...

This book provides a detailed account of the physico-chemical properties and biological functions of the outer membrane vesicles (OMVs) of different pathogenic and non-pathogenic Gram-negative bacteria. It also includes an authentic record of the first...

We are celebrating this year the hundred years´ anniversary of allergen-specific immunotherapy. In 1911 Leonard Noon published his seminal work "Prophylactic inoculation against hay fever" describing his attempts to achieve active immunity against "grass...

This volume of Current Topics in Microbiology and Immunology covers diverse topics related to intradermal immunization. The chapters highlight the effectiveness of intradermal immunization in experimental animal models or in clinical practice, all...

Adaptive immune responses serve as a key defense mechanism for the control of infections in vertebrates. Immune responses must be of sufficient strength to contain invading pathogens, antigen specific responses require regulatory mechanisms to ensure...

The means by which non-enveloped viruses penetrate cellular membranes during cell entry remain poorly defined. Recent findings indicate several members of this group share a common mechanism of membrane penetration in which the virus particle undergoes...

The human immune system is a complex network of tissues and organs dispersed throughout the body. Immunology, as one of the most rapidly evolving fields in bio¬medical research, has to date covered the essential cellular and...

Two-Photon Imaging of the Immune System: A Custom Technology Platform for High-Speed, Multicolor Tissue Imaging of Immune Responses.- Visualizing Intermolecular Interactions in T Cells.- Multiscale analysis of T cell activation: correlating in vitro and...

Our gut is colonized by numerous bacteria throughout our life, and the gut epithelium is constantly exposed to foreign microbes and dietary antigens. Thus, the gut epithelium acts as a barrier against microbial invaders and is...

Recent years have seen unprecedented outbreaks of avian influenza A viruses. In particular, highly pathogenic H5N1 viruses have not only resulted in widespread outbreaks in domestic poultry, but have been transmitted to humans,...

Although the utility of human antibodies as medical therapeutics for cancer and immune diseases has been well-established, it is only beginning to be realized for the treatment of viral infectious diseases. Polyclonal...

This volume features contributions from participants of the ESRF symposium on Immunotherapy in 2020-Visions and Trends for Targeting Inflammatory Diseases held in Potsdam near Berlin, Germany, in October 2006. The symposium...

Approximately 60% of all hospital-associated infections, over one million cases per year, are due to biofilms that have formed on indwelling medical devices. Device-related biofilm infections increase hospital stays and add...

It has been clear for a long time that after transplantation of a lymphoid organ, hematopoietic stem cells can regenerate the compartments of the organ, provided that the rest of its architecture - the strome, the epithelia and...

In September 1998 experts from 19 countries came together for an interdisciplinary discussion of the function of animal peroxidases, a family of enzymes embracing myeloperoxidase, eosinophil peroxidase, thyroid peroxidase and...

5 Function of Splenic Compartments . . . . . . . . . . . . . . . 45 5. 1 Splenic White Pulp Compartments during Primary T Cell-Dependent Antibody Responses against Protein Antigens . . . . . . . . . . . . . . . . . . . . . . . ...

Advanced renal cell carcinoma is refractory to nearly forms of systemic therapy. For this reason the last decade has seen numerous research groups working on immunotherapeutic s trategies against it. Immunotherapy of Renal...

The clinical and experimental effects of cytokines have been realized for a long time. The clinical effects of tumor necrosis factor were noted almost 100 years ago. The basic biological effects of interferons and the ...

The 1st International Workshop in the Molecular and Cell Biology of Autoan­ tibodies and Autoimmunity is convened at a time when recombinant DNA tech­ niques have yielded the first set of data providing initial glimpses of...

You see things, and sa)' why? But I dream 1hings that never were, and I say, 11'hy 110t? George Bernhard Shaw Far ahead of his time, June 1st, 1909, Alexander Maximov communicated in a lecture, given in the Charite in Berlin,...

Distinguished scientists and members of the medical profession discuss the research and development of safe and suitable drugs for the long-term treatment of chronic diseases. The book provides an up-to-date survey on ...

1. 1 Historical Aspects and Terminology Granulated metrial gland (GMG) cells are readily identified by their cytoplasmic granules and were observed a number of years before the term "metrial gland" was introduced. A series of...

In the past, research in cancer immunology has produced informa­ tion important for other medical disciplines. It helped, for example, in formulating the laws of immunogenetics and in achieving a better understanding of the...

The aberrant replication pathway of foamy viruses distinguishes them from all other retroviruses. Many details have been accumulated over the past ten or so years. Most of the findings on foamy viruses were obtained by research...

Allergy is one of the major health problems of most modern societies. Allergic diseases have increased in prevalence during the last decades; the reasons for this increase are unknown, there are only hypothetical concepts for...

W. B. Harrison, B. A. C. Dijkmans During the last decade intervention has been instituted for all kinds of disease- even in a premorbid state, as early as possible, to control the activity of the disease, to avoid further...

In spite of the protection of the CNS there are situations where immune responses occur due to different disease processes. While antigen-specific cells of the adaptive immune response are not normally functional in the CNS...

It has been known for a number of years that not only pathogenicity islands but also plasmids and bacteriophages are able to carry genes whose products are involved in pathogenic processes. Accordingly, such elements and their...

Natural Killer (NK) cells are large granular lymphocytes of the innate immune system. They are widespread throughout the body, being present in both lymphoid organs and non-lymphoid peripheral tissues. NK cells are involved in...

The therapeutic options for the treatment of multiple sclerosis (MS) and other neurodegenerative and traumatic diseases such as spinal cord injury, Alzheimer's, Parkinson's disease, etc. , have undergone enormous progress over...

Following its tradition of promoting novel areas of scienti?c discourse, the Ernst Schering Research Foundation (ESRF) hosted this workshop on chronic viral and in?ammatory cardiomyopathy. In late October 2004, scientists from...

According to the World Health Organization, approximately one third of the world's population is latently infected with Mycobacterium tuberculosis (M. tb [LTBI]), of whom about 9 million have active tuberculosis (TB). It is estimated that approximately 2...

This new edition continues to illustrate the power of biological data in knowledge discovery. It describes biological data types and representations with examples for creating a workflow in bioinformation discovery. The concepts in knowledge discovery...

Leading researchers are specially invited to provide a complete understanding of a key topic within the multidisciplinary fields of physiology, biochemistry and pharmacology. In a form immediately useful to scientists, this periodical aims to filter,...

Our own experience shows that there is no simple, yet of good scientific and clinical quality guide for practitioners and patients on gastrointestinal diseases. In the proposed book we will cover a vast area in the field, from GI tract physiology to...

Insect-transmitted rickettsiales diseases are significant sources of morbidity and mortality all over the world. Their incidence has been increasing in recent years in large part due to climate change and the movement of animals carrying the insect...