Molecular biology Books

Fibrogenesis: Cellular and Molecular Basis is the first volume to provide a synopsis of the rapid progress that has been documented in fibrogenesis over last couple of years, which significantly enhanced our understanding of the pathomechanisms of...

In this volume, the major metabolic alterations identified in cancer and tumor-associated cells are explored, including discussions of former and emerging approaches to drug development in targeting cancer cell metabolism. The metabolic network in cells...

Adult Stem Cells, second edition, takes a critical look at issues concerning the developmental or differentiation potential for a variety of tissue types and for specific adult stem cell types. Since the first edition appeared...

This book highlights the importance of phytochemicals and mitochondria in cancer prevention and therapy. Recent scientific discoveries have identified that naturally occurring biologically active compounds (i.e. phytochemicals) target multiple steps of...

In view of rapidly growing research in the deregulation of proteases and their impact in human health and diseases, this book will highlight existing and emerging research in this exciting area. In-depth critical ...

Synapses underlie rapid and flexible neural communication in the brain and they hold the key to understanding higher brain functions in health and disease. Because they are very small and highly dynamic, it is very difficult to...

Currently, there are tremendous advances being made in understanding the basic science of both the structure and function of botulinum neurotoxins. This knowledge is opening up opportunities in regard to both therapeutic uses and treatment and protection...

This book puts the ethics, policy and politics of stem cells into context in a way that helps readers understand why past and current issues have developed the way they have and what the implications are for their work going...

Asthma is a chronic relapsing airways disease that represents a major public health problem worldwide. Intermittent exacerbations are provoked by airway mucosal exposure to pro-inflammatory stimuli, with RNA viral infections or...

​​​The imbalance between rapidly proliferating tumor cells and inadequate and inefficient tumor vasculature leads to a decrease in oxygen levels (hypoxia and/or anoxia) in tumor tissues. Intra-tumor hypoxia profoundly affects the biological behavior of...

The discovery of microRNAs and its role as gene expression regulators in human carcinogenesis represents one of the most important scientific achievements of the last decade. More recently, other non-coding RNAs have been discovered and its implications...

Stem Cell therapy for lysosomal diseases (LSDs) is developing rapidly. This volume discusses the history, current practice and future perspectives of stem cells in inborn errors of metabolism (IEM) and provides an international...

Starting with discussion of basic concepts and the molecular mechanisms of necrosis, this book looks first at several forms of necrotic cell death that have been identified, including necroptosis, autophagic cell death, and...

This is a comprehensive guide to single-stranded RNA phages (family Leviviridae), first discovered in 1961. Special attention will be devoted to modern applications of the RNA phages and their products in nanotechnology, vaccinology, gene discovery,...

Discussing origins, including the Big Bang and the origin of the elements, this book provides evidence that the molecules of life are produced in outer space and how the SNAAP model purports to explain that origin. It is aimed at the upper undergraduate...

This book "Alternative Splicing and Cancer" explores the crucial role alternative splicing, a post-transcriptional process, plays in human health and diseases, particularly cancer.

Mitochondrial research has exploded over the last ~150 years. This book gives an amazing view on a conceptual change in our understanding of mitochondrial biology. It becomes clear that mitochondria are extremely dynamic in nature controlling life at...

In a new preface to this special edition of his critically acclaimed memoir, Francois Jacob recalls the events that brought him to Cold Spring Harbor Laboratory in the early 1960's and taught him much about phage biology and the informal ways of American...

Bioinformatics for Oral Cancer: Current Insights and Advances serves as a comprehensive guide offering a multifaceted landscape of oral cancer research and bioinformatics. Readers will uncover a wealth of knowledge, starting with foundational chapters...

Marine environment is a habitant for several species and significantly plays an essential role in the food cycle and climate regulation. Several species including fish and invertebrates that are used as food for humans. Marine larvae species also contain...

CRISPR/Cas endonuclease has emerged, as a powerful genetic engineering tool. It is simple yet highly affordable and robust. This book provides a basic introduction to the mechanism and architecture of the CRISPR/Cas.

Showcasing the recent progresses of the field, Cyclic Nucleotide Signaling covers the major tools and methodologies used in various areas of research. The majority of the chapters are protocol oriented, with the goal of providing clear directions for...

Salinity stress currently impacts more than 80 million hectares of land worldwide and more arable land is likely to be impacted in the future due to global climate changes. Managing Salt Tolerance in Plants: Molecular and Genomic Perspectives presents...

Published in 1975: This volume contains the completed section of the Handbook of Biochemistry and Molecular Biology with data pertaining to Lipids, Carbohydrates, and Steroids.

If our bodies could do more things, would our lives be better? Genome editing is a rapidly developing technology that can modify human genes. It can cure heritable diseases, but we could even make certain genetic "improvements" to healthy people. Should...

Natural scientists perceive and classify organisms primarily on the basis of their appearance and structure- their form , defined as that characteristic remaining invariant after translation, rotation, and possibly reflection of the object. The...

This book provides a comprehensive and in-depth discussion on the development of herbicide resistance during the past 50 years, emphasizing the biochemical pathways of herbicide resistance in weeds. It discusses the principles of plant genetics,...

DNA repair is a rapidly advancing field in biology. DNA repair systems represent a major defense mechanism against environmental and intracellular damaging agents, such as sunlight, ionizing radiation, and reactive oxygen species. With contributions from...

Regulation of Permeability Across the Blood‑Brain Barrier.- Drug Transporters at Brain Barriers: Expression and Regulation by Neurological Disorders.- The Blood‑Retina Barrier: Tight Junctions and Barrier Modulation.- The Inner Blood‑Retinal Barrier:...

Photopigments are molecules that react to light and mediate a number of processes and behaviours in animals. Visual pigments housed within the photoreceptors of the eye, such as the rods and cones in vertebrates are the best...

Multiple myeloma is a plasma cell malignancy characterized by complex heterogenous cytogenetic abnormalities that accounts for 1.4% of all cancers, and approximately 10% of hematologic malignancies. The clinical manifestations...

Germ cells in sexually reproducing metazoa, through the germline lineage, are the route by which genetic material and cytoplasmic constituents are passed from one generation to the next in the continuum of life. Chapters in this book review germ cell...

Mitochondrial cytopathies are mutations in the inherited maternal mitochondrial genome, or the nuclear DNA-mutation. Mitochondrial respiratory chain disorders (RCD) are a group of genetically and clinically heterogeneous diseases, due to the fact that...

In multicellular organisms, communication between cells involves secretion of proteins that bind to receptors on neighboring cells. While this has been well documented, another mode of intercellular communication has recently...

Depite the rapid expansion of the field of biophysics, there are very few books that comprehensively treat specific topics in this area. Recently, the field of single molecule biophysics has developed very quickly, and a few books specifically treating...

This book is written by leading researchers in the fields about the intersection of genetics and metabolomics which can lead to more comprehensive studies of inborn variation of metabolism.

This book is being planned as a tribute to Dr. Victor A. McKusick (1921-2008), who is well known as the "father of medical genetics". He was long associated with the Johns Hopkins University School of Medicine, first as a...

Sphingolipid Metabolism and Analysis in Metabolic Disease.- Sphingolipids and Cardiovascular Diseases: Lipoprotein Metabolism, Atherosclerosis and Cardiomyopathy.- Heart Sphingolipids in Health and Disease.- Blood Sphingolipids in Homeostasis and...

Mast Cell Biology: Introduction And Overview.- Mast Cell Progenitor Trafficking And Maturation.- Monomeric IgE And Mast Cell Development, Survival And Function.- Mast Cell Apoptosis And Survival.- Regulators Of Ca2+ Signaling In Mast Cells: Potential...