The idea of formulating Fast Dissolving Tablets of Febuxostat is to provide an acceptable and practical approach for the objectives of faster disintegrating and dissolution characteristics. In the current work Fast Dissolving Tablets of Febuxostat were prepared by sublimation technique after preparing solid dispersion of Febuxostat in which co- precipitation gives high solubility in ratio of 1:0.5:1.2 (Drug: PEG 6000: Mannitol) , using sodium starch glycolate, croscarmellose sodium, kyron T -134 and kyron T-314. All the Fast Dissolving Tablets of Febuxostat were subjected to thickness, diameter, hardness, friability, weight variation, disintegration time, wetting time, water absorption ratio and drug content uniformity.
The idea of formulating Fast Dissolving Tablets of Febuxostat is to provide an acceptable and practical approach for the objectives of faster disintegrating and dissolution characteristics. In the current work Fast Dissolving Tablets of Febuxostat were prepared by sublimation technique after preparing solid dispersion of Febuxostat in which co- precipitation gives high solubility in ratio of 1:0.5:1.2 (Drug: PEG 6000: Mannitol) , using sodium starch glycolate, croscarmellose sodium, kyron T -134 and kyron T-314. All the Fast Dissolving Tablets of Febuxostat were subjected to thickness, diameter, hardness, friability, weight variation, disintegration time, wetting time, water absorption ratio and drug content uniformity.
Oral drug delivery has been known for decades the most widely utilized route for administration among all the route that have been explored for systemic delivery of drugs via various pharmaceutical...
Chlorpromazine HCl and Promethazine HCl are potent anti-emetic. The central antimuscarinic actions of antihistamines are probably responsible for their anti-emetic effects. Fast dissolving tablets of...
The idea of formulating Fast Dissolving Tablets is to provide an acceptable and practical approach for the objectives of faster disintegrating and dissolution characteristics.In the current work Fast...
The present investigation involves formulation and evaluation of fast dissolving tablet of clopidogrel, which is used to prevent coronary disorder. Platelet aggregation is part of the sequence events...
Metoprolol Tartrate is a β-blocker drug indicated for the treatment of angina, prevention of myocardial infarction, Essential hypertension; It has low bioavailability of about 40% due to hepatic...
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