Structure: Nuclear Magnetic Resonance Studies of ThrombinFibrinopeptide and ThrombinHirudin Complexes (F. Ni et al.). ESR and Flourescence Studies of Thrombin Active Site Conformation (L.J. Berliner). Biochemistry: Synthetic Substrates and Inhibitors of Thrombin (J.C. Powers, C.M. Kam). Regulation of Thrombin by Antithrombin and Heparin Cofactor II (S.T. Olson, I. Björk). Hirudin Interactions with Thrombin (S.R. Stone, J.M. Maraganore). Physiology: Functional Domains in Thrombin Outside the Catalytic Site (R. BarShavit et al.). Post Clotting Cellular Effects of Thrombin Mediated by Interaction with HighAffinity Thrombin Receptors (D.H. Carney). Regulation of ThrombinInduced Endothelial Barrier Dysfunction and Prostaglandin Synthesis (J.G.N. Garcia et al.). 3 additional articles. Index.
Structure: Nuclear Magnetic Resonance Studies of ThrombinFibrinopeptide and ThrombinHirudin Complexes (F. Ni et al.). ESR and Flourescence Studies of Thrombin Active Site Conformation (L.J. Berliner). Biochemistry: Synthetic Substrates and Inhibitors of Thrombin (J.C. Powers, C.M. Kam). Regulation of Thrombin by Antithrombin and Heparin Cofactor II (S.T. Olson, I. Björk). Hirudin Interactions with Thrombin (S.R. Stone, J.M. Maraganore). Physiology: Functional Domains in Thrombin Outside the Catalytic Site (R. BarShavit et al.). Post Clotting Cellular Effects of Thrombin Mediated by Interaction with HighAffinity Thrombin Receptors (D.H. Carney). Regulation of ThrombinInduced Endothelial Barrier Dysfunction and Prostaglandin Synthesis (J.G.N. Garcia et al.). 3 additional articles. Index.
Chemical Biology of Thrombin is a comprehensive review of thrombin as regulatory protease, perhaps one of the most important enzymes in hemostasis. It focuses on work from 1970's to the present time...
In one generation, the numerous factors involved in blood coagulation have become real protein entities, isolated in pure form, expressed by recombinant DNA techniques, and subjected to structure...
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