Simultaneous Estimation of Sumatriptan Succinate, Naproxen, Domperidone

Quality is important in every product or service, but it is vital in medicine, as it involves life, so there should not be any compromises to quality of drug products. Secondly, to maintain the quality of drugs is a regulatory and mandatory requirement and lastly it is crucial for business in modern and competitive market also. Quality of drugs can only be maintained by analyzing it using analytical method with high degree of accuracy and precision and should satisfy all other validation parameters. The accuracy and precision depends upon the relative and absolute errors. Errors will be minimized if the method is simple. So the simplicity of the method can be indirectly related to accuracy and precision. Therefore simplicity of the method should be one of the prime considerations while developing analytical method. The aim of the study is to develop and validate HPLC assay for rapid determination of selected antimigraine drugs of category 5-HT1 agonist, NSAIDs and antiemetics in combined dosage form. The drugs under these categories are widely used for the treatment of migraine either as monotherapy or as multiple drug therapy for better efficacy. As there is no established method