The goal of this work is summarize the contribution that insertional mutagenesis has made to our understanding of cancer. A variety of insertional mutagens are presented that have been used to study a variety of tumor types in several model organisms. In addition, the impact of insertional mutagenesis in several gene therapy trials is discussed along with strategies to avoid such complications in future clinical trials.
Insertional Mutagenesis Strategies in Cancer Genetics
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The goal of this work is summarize the contribution that insertional mutagenesis has made to our understanding of cancer. A variety of insertional mutagens are presented that have been used to study a variety of tumor types in several model organisms. In addition, the impact of insertional mutagenesis in several gene therapy trials is discussed along with strategies to avoid such complications in future clinical trials.
The present volume contains papers presented on the occasion of the Ichthyological Symposium on Genetics and Mutagenesis held on October 13 through 15, 1972 at the Biology Institute of the...
MutagenesisThe Mutants roam the world and will stop at nothing to eliminate those who oppose them. David and his companions, Lena and Hue, are beset with grief over Rocco's death. He was the glue...
In vitro mutagenesis remains a critical experimental approach for investigating gene and protein function at the cellular level. This volume provides a wide variety of updated and novel approaches...
This book is something which almost accidentally has developed very differently from how it was initially planned. The intention was to elaborate the part played by the immune system in ageing with...
Mutagenesis is a vast field of study. The difficulty in comprehension of biochemical and molecular foundations of healthy life, and enthusiasm to find easy explanation demands advancement of skills...
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