Trending Bestseller

Induced Pluripotent Stem Cells

Sibel Yildirim

No reviews yet Write a Review
Paperback / softback
01 December 2011
$119.00
In Stock: Ships in 3-5 Days
In Stock: Ships in 7-9 Days
Hurry up! Current stock:

Induced Pluripotent Stem (iPS) cells are mature cells that have been genetically reprogrammed so that they return to their embryonic state. It is not yet known if iPS stem cells and embryonic stem cells differ significantly. Today many fundamental belief systems in biology are shifting towards accepting that mature body cells can be reverted to an embryonic state without the help of eggs or embryos. With their changed identities, iPS cells are then ready to serve as new tools for research in the fields of disease pathogenesis, drug discovery, oncology, and cell transplantation. One example of this would be using iPS from a patient's mature cells to repair damaged tissue; it is thought that there would be very low incidence of rejection of the 'new' tissue in these cases. For the last four years, this therapeutic promise has been studied by hundreds of researchers worldwide in an effort to understand the ability of these cells to reverse their biological clocks.

Table of contents:

Introduction.- Pluripotent Cells.- Pluripotent Cells.- Transcriptional Networks and Signaling Pathways of Pluripotency.- Induced Pluripotent Stem Cells (iPSCs).- Generation the First iPSCs.- Reprogramming.- Molecular Mechanisms of Pluripotency.- Steps in Reprogramming.- Mechanisms in Reprogramming.- Dynamics of Direct Reprogramming.- Epigenetic Modifications.- Similarities and Differences between iPSCs and ESCs.- Modeling Disease in a Dish.- Disease Specific iPSCs.- Choosing Cell Sources.- Identification of iPSC Colonies.- Characterization of Genetic Mutation.- iPSCs Differentiation into Desired Cell Types.- Challenges to Therapeutic Potential of Human iPS Cells.- Is Reprogramming Necessary for Regenerative Therapies?.- New Approach to Understand the Biology of Stem Cells.- Health vs. Disease.- Changed Paradigm: Reprogramming as Rare but Robust Process.- From Reductionism to Wholeness.- More Future Considerations.- Conclusion.

This product hasn't received any reviews yet. Be the first to review this product!

$119.00
In Stock: Ships in 3-5 Days
In Stock: Ships in 7-9 Days
Hurry up! Current stock:

Induced Pluripotent Stem Cells

$119.00

Description

Induced Pluripotent Stem (iPS) cells are mature cells that have been genetically reprogrammed so that they return to their embryonic state. It is not yet known if iPS stem cells and embryonic stem cells differ significantly. Today many fundamental belief systems in biology are shifting towards accepting that mature body cells can be reverted to an embryonic state without the help of eggs or embryos. With their changed identities, iPS cells are then ready to serve as new tools for research in the fields of disease pathogenesis, drug discovery, oncology, and cell transplantation. One example of this would be using iPS from a patient's mature cells to repair damaged tissue; it is thought that there would be very low incidence of rejection of the 'new' tissue in these cases. For the last four years, this therapeutic promise has been studied by hundreds of researchers worldwide in an effort to understand the ability of these cells to reverse their biological clocks.

Table of contents:

Introduction.- Pluripotent Cells.- Pluripotent Cells.- Transcriptional Networks and Signaling Pathways of Pluripotency.- Induced Pluripotent Stem Cells (iPSCs).- Generation the First iPSCs.- Reprogramming.- Molecular Mechanisms of Pluripotency.- Steps in Reprogramming.- Mechanisms in Reprogramming.- Dynamics of Direct Reprogramming.- Epigenetic Modifications.- Similarities and Differences between iPSCs and ESCs.- Modeling Disease in a Dish.- Disease Specific iPSCs.- Choosing Cell Sources.- Identification of iPSC Colonies.- Characterization of Genetic Mutation.- iPSCs Differentiation into Desired Cell Types.- Challenges to Therapeutic Potential of Human iPS Cells.- Is Reprogramming Necessary for Regenerative Therapies?.- New Approach to Understand the Biology of Stem Cells.- Health vs. Disease.- Changed Paradigm: Reprogramming as Rare but Robust Process.- From Reductionism to Wholeness.- More Future Considerations.- Conclusion.

Customers Also Viewed

Discover Books for Every Interest at BookLoop

Discover your next great read at BookLoop, Australia's trusted online bookstore offering a vast selection of titles across various genres and interests. Whether you're curious about what's trending or searching for graphic novels that captivate, thrilling crime and mystery fiction, or exhilarating action and adventure stories, our curated collections have something for every reader. Delve into imaginative fantasy worlds or explore the realms of science fiction that challenge the boundaries of reality.

Books on Hobbies, Crafts, Gardening, and More

For those with a green thumb, our comprehensive range of gardening books provides insights and tips for all levels of enthusiasts. If you're aiming to enhance your financial acumen, our selection of finance, business, and management books offers valuable knowledge from industry experts. Craft lovers will appreciate our assortment of handicrafts, decorative arts, and crafts books, perfect for inspiring your next project. Engage your mind with our collection of hobbies, quizzes, and games books, or explore the mystical with our fortune-telling and divination guides.

Transport, Contemporary Fiction, and Picture Books for Kids

Transportation aficionados can immerse themselves in our extensive transportation books, including detailed works on road and motor vehicles. Young readers are not left out, with a delightful array of picture books and early learning concepts designed to educate and entertain. Fans of contemporary narratives will find compelling stories in our contemporary fiction section. Embark on epic journeys with our fantasy and science fiction titles, or gain inspiration from real-life tales in our biographies and true stories collection. Health-conscious readers can explore our health and wholefood cooking books, focusing on specific diets and conditions.

School Books, Teacher Resources, and Academic Textbooks

Textbooks for Primary, Secondary, and Higher Education

BookLoop proudly supports the educational needs of students and schools across Australia. Our textbook collection includes school books and teacher resources for every phase from primary school books, secondary school books, and essential titles for TAFE courses, vocational training, and university study. Each book is selected to align with curriculum outcomes and classroom needs, making it easy for schools and teachers to plan ahead.

Teacher Resources and Classroom Support Materials

From structured lesson planning to engaging student activities, our wide range of school books and teacher resources provides essential tools for educators. You’ll also find dedicated school and preschool teacher materials designed for early years education, classroom support, and intervention. Teachers can access a reliable selection of workbooks, literacy and numeracy programs, assessment tools, and professional development guides all in one place.

Books for Early Learning Centres and Childcare Professionals

Support the earliest stages of education with our curated range of early childhood care and education books. These titles are ideal for early learning centres, preschools, and childcare settings, offering age-appropriate resources that build foundational skills in literacy, numeracy, and emotional development. Families and educators alike trust our resources for quality, clarity, and classroom effectiveness.

Bulk Book Orders for Schools and Educational Institutions

We make bulk school book orders simple and efficient. Schools, libraries, and early learning centres can rely on BookLoop for competitive pricing, fast shipping, and expert support when sourcing large quantities of textbooks and educational materials. Whether you’re restocking for a new term or ordering resources for an entire class, our bulk ordering system ensures convenience and accuracy every step of the way.

Stay Up to Date with Book Trends

Explore our new releases for the most recent additions in romance books, fantasy books, graphic novels, crime and mystery books, science fiction books as well as biographies, cookbooks, self help books, tarot cards, fortunetelling and much more. With titles covering current trends, booktok and bookstagram recommendations, and emerging authors, BookLoop remains your go-to local australian bookstore for buying books online across all book genres.

Explore the Latest and Most Loved Books

Stay updated with the literary world by browsing our trending books, featuring the latest bestsellers and critically acclaimed works. Explore titles from popular brands like Minecraft, Pokemon, Star Wars, Bluey, Lonely Planet, ABIA award winners, Peppa Pig, and our specialised collection of ADHD books. At BookLoop, we are committed to providing a diverse and enriching reading experience for all.