How Radiotherapy and Chemotherapy effect the Blood Parameters of Cancer Patients

Master's Thesis from the year 2010 in the subject Medicine - Neoplasms, Oncology, grade: A, University of Sindh (Biochemistry), language: English, abstract: The whole research work was conducted to investigate the effect of radiotherapy and chemotherapy in cancer patients by complete blood picture, anthropometric and physiological measurement. Complete blood picture include RBCs, Hb, MCV, MCHC, MCH, WBCs (Neutrophils, Lymphocytes, Eosinophils, Monocytes, Basophiles) and platelets. Anthropometric measurement include age, height, and weight. Physiological measurement includes systolic and diastolic blood pressure and pulse rate measurement. Comparison between control and cancer patient samples shows that RBCs have no significant difference in their levels but some cancer which treated with radiotherapy and chemotherapy may shows anemia. Hb comparison of control and shows difference in their levels. Hb decreases in cancer patients (due to diminished partial pressure of O2) but could be increases whit use of erythropoietin in cancer patients. An absolute indices (MCV, MCH, MCHC) decrease in cancerous patients. Chemotherapeutic treatment shows decrease in WBCs and platelets, it is also seen in leukemia, lymphoma, or multiple myolema. Neutropenia and thrombocytopenia also observed. Weight and height also decreased in cancer patients. Systolic and diastolic blood pressure is increases in cancer patients, and pulse rate is decreases in cancer patients