Deoxynucleoside Analogs in Cancer Therapy

Nucleoside Transport into Cells: The Role of Nucleoside Transporters SLC28 and SLC29 in Cancer Chemotherapy Marcal Pastor-Anglada and F. Javier Casado The Role of Deoxycytidine Kinase in DNA Synthesis and Nucleoside Analog Activation Maria Staub and Staffan Eriksson Deoxynucleoside Kinases and Their Potential Role in Deoxynucleoside Cytotoxicity Birgitte Munch-Petersen and Jure Piskur Nucleotidases and Nucleoside Analog Cytotoxicity Sally Anne Hunsucker, Beverly S. Mitchell, and Jozef Spychala Pumping Out Drugs: The Potential Impact of ABC Transporters on Resistance to Base, Nucleoside, and Nucleotide Analogs Piet Borst and Peter Wielinga Cytosine Arabinoside: Metabolism, Mechanisms, of Resistance, and Clinical Pharmacology Isabelle Hubeek, G. J. L. Kaspers, G Ossenkoppele, and G. J. Peters Clofarabine: Mechanisms of Action, Pharmacology, and Clinical Investigation Varsha Gandhi and William Plunkett L-Nucleosides as Chemotherapeutic Agents Giuseppe Gumina, Youhoon Chong, and Chung K. Chu Troxacitabine: A Deoxycytidine Nucleoside Analogue With Potent Antitumor Activity Henriette Gourdeau and Jacques Jolivet 9-b-D-arabinofuranosylguanine Sophie Curbo Gemcitabine: Mechanism of Action and Resistance A. M. Bergman and G.J. Peters Clinical Activity of Gemcitabine as a Single Agent and in Combination J. R. Kroep, GJ Peters, and RA Nagourney Nucleoside Radiosensitizers Donna S. Shewach and Theodore S. Lawrence NONMEM Population Models of Cytosine Arabinoside and Flubaradine Phosphate in Pediatric Patients with Leukemia Vassilios I. Avramis The cycloSal-Nucleotide Delivery System: Development of Chemical Trojan Horses as Antiviral Agents Chris Meier, Jan Balzarini, and Astrid Meerbach Purine and Pyrimidine Based Analogs and Suicide GeneTherapy Zoran Gojkovic 3'-deoxy-3'- Fluorothymidine as a Tracer if Proliferation in Positron Emission Tomography