The book provides an introduction and comprehensive information regarding chromatin remodelling. Chromatin remodelling is used to describe the dynamic modification of chromatin architecture governed by histone-modifying enzymes, non-histone DNA-binding proteins, chromatin remodelling complexes and noncoding RNAs. Various diseases and disorders such as cancer, autism etc. have been related to the breakdown of these control mechanisms by genetic, environmental or microbial factors. The mechanisms through which these factors work are evolving as a new and interesting genre of research and would help in discovering new ways of treatments of these diseases. This book covers recent developments in the domain of biology dealing with gene regulation, chromatin structure, DNA recovery and human diseases.
The book provides an introduction and comprehensive information regarding chromatin remodelling. Chromatin remodelling is used to describe the dynamic modification of chromatin architecture governed by histone-modifying enzymes, non-histone DNA-binding proteins, chromatin remodelling complexes and noncoding RNAs. Various diseases and disorders such as cancer, autism etc. have been related to the breakdown of these control mechanisms by genetic, environmental or microbial factors. The mechanisms through which these factors work are evolving as a new and interesting genre of research and would help in discovering new ways of treatments of these diseases. This book covers recent developments in the domain of biology dealing with gene regulation, chromatin structure, DNA recovery and human diseases.
Chromatin is of central importance to gene regulation in eukaryotes. Reflecting this singular role for chromatin, numerous approaches have evolved in the laboratory over the past three decades to...
The delicate nature of reproduction is evidenced by the fact that the female gamete is notorious for having high rates of chromosomal abnormalities. It is estimated 10-25% of all human conceptions...
This volume provides cutting-edge techniques to further the study chromatin biology. Chapters include both novel and well-established methods for the analysis of DNA-associated proteins, DNA...
Lex A'llure is a young visionary who aims to use her talents and creativity to plant a seed of inspiration, hope, and healing into everyone that she encounters. Whether it's through her writing,...
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