sale
Choroid Plexus Pharmacology
Choroid Plexus Pharmacology
Choroid Plexus Pharmacology
Choroid Plexus Pharmacology
Choroid Plexus Pharmacology
Choroid Plexus Pharmacology
Trending Bestseller

Choroid Plexus Pharmacology

Carsten H. Baehr

No reviews yet Write a Review
Paperback / softback
10 July 2008
RRP: $94.75
$76.00
Ships in 5–7 business days
Hurry up! Current stock:
icon Share icon Share
Description  
The choroid plexus (CP) epithelium forms the blood-cerebrospinal fluid (CSF) barrier and, along with the blood-brain barrier, maintains the fluid environment of the brain. The CP not only secretes CSF, but also transports potentially toxic xenobiotics and waste products of neural metabolism to the blood for eventual clearance in kidney and liver. However, studying CP is difficult, due to complex morphology, ana­tomical location and small size of the tissue and little is known about the molecular mechanisms, functional complexity and hormonal regu­lation of organic anion secretion. To further elucidate the underlying mechanisms of organic anion transport across CP epithelium, a pri­mary porcine CP cell culture model was established and characterized. Organic anion transport was studied in a mammalian (rat), a comparative elasmobranch and in an in vitro porcine cell culture mo­del, using model compound fluorescein-methotrexate. Organic anion transport was shown to be a specific and concentrative, Na-ion dependent and metabolism-dependent two-step process. Finally, for the first time, the studies demonstrated that organic anion transport is regulated by protein kinase (PK) C and PKA.
Customer reviews  

This product hasn't received any reviews yet. Be the first to review this product!

Write a Reviews
Flat Rate Shipping  
Easy Returns  
RRP: $94.75
$76.00
Ships in 5–7 business days
Hurry up! Current stock:
icon Share icon Share
Flat Rate Shipping  
Easy Returns  

Choroid Plexus Pharmacology

RRP: $94.75
$76.00

Description

The choroid plexus (CP) epithelium forms the blood-cerebrospinal fluid (CSF) barrier and, along with the blood-brain barrier, maintains the fluid environment of the brain. The CP not only secretes CSF, but also transports potentially toxic xenobiotics and waste products of neural metabolism to the blood for eventual clearance in kidney and liver. However, studying CP is difficult, due to complex morphology, ana­tomical location and small size of the tissue and little is known about the molecular mechanisms, functional complexity and hormonal regu­lation of organic anion secretion. To further elucidate the underlying mechanisms of organic anion transport across CP epithelium, a pri­mary porcine CP cell culture model was established and characterized. Organic anion transport was studied in a mammalian (rat), a comparative elasmobranch and in an in vitro porcine cell culture mo­del, using model compound fluorescein-methotrexate. Organic anion transport was shown to be a specific and concentrative, Na-ion dependent and metabolism-dependent two-step process. Finally, for the first time, the studies demonstrated that organic anion transport is regulated by protein kinase (PK) C and PKA.

Customers Also Viewed

Buy Books Online at BookLoop

Discover your next great read at BookLoop, Australiand online bookstore offering a vast selection of titles across various genres and interests. Whether you're curious about what's trending or searching for graphic novels that captivate, thrilling crime and mystery fiction, or exhilarating action and adventure stories, our curated collections have something for every reader. Delve into imaginative fantasy worlds or explore the realms of science fiction that challenge the boundaries of reality. Fans of contemporary narratives will find compelling stories in our contemporary fiction section. Embark on epic journeys with our fantasy and science fiction titles,

Shop Trending Books and New Releases

Explore our new releases for the most recent additions in romance books, fantasy books, graphic novels, crime and mystery books, science fiction books as well as biographies, cookbooks, self help books, tarot cards, fortunetelling and much more. With titles covering current trends, booktok and bookstagram recommendations, and emerging authors, BookLoop remains your go-to local australian bookstore for buying books online across all book genres.

Shop Best Books By Collection

Stay updated with the literary world by browsing our trending books, featuring the latest bestsellers and critically acclaimed works. Explore titles from popular brands like Minecraft, Pokemon, Star Wars, Bluey, Lonely Planet, ABIA award winners, Peppa Pig, and our specialised collection of ADHD books. At BookLoop, we are committed to providing a diverse and enriching reading experience for all.