Many new drugs on the market are chiral compounds, that is, they can exist in two non-superimposable mirror-image forms. Asymmetric catalysis encompasses a large variety of processes for obtaining such compounds. The performance of the catalyst in those processes largely depends on the ligand that makes up the catalyst. This book describes the most relevant ligand libraries for some key processes, including an overview of the state of art and the key mechanistic aspects that favor a high catalytic performance.
Key Features:
The book presents historical content from the time of discovery for each family of ligands.
Provides a description of the synthetic route and the ligand library's application in various catalytic asymmetric reactions
Suitable as supplementary reading for courses targeting the design, synthesis and application of chiral catalysts, asymmetric catalysis and sustainable production
Edited by a distinguished scientist in the field, the book has a diverse audience including research groups in homogeneous catalysis, particularly asymmetric transformations
Many new drugs on the market are chiral compounds, that is, they can exist in two non-superimposable mirror-image forms. Asymmetric catalysis encompasses a large variety of processes for obtaining such compounds. The performance of the catalyst in those processes largely depends on the ligand that makes up the catalyst. This book describes the most relevant ligand libraries for some key processes, including an overview of the state of art and the key mechanistic aspects that favor a high catalytic performance.
Key Features:
The book presents historical content from the time of discovery for each family of ligands.
Provides a description of the synthetic route and the ligand library's application in various catalytic asymmetric reactions
Suitable as supplementary reading for courses targeting the design, synthesis and application of chiral catalysts, asymmetric catalysis and sustainable production
Edited by a distinguished scientist in the field, the book has a diverse audience including research groups in homogeneous catalysis, particularly asymmetric transformations
Chiral molecules are molecules that come in left and right handed forms - they are mirror images of each other and behave differently in the body. This important book show chemists how to prepare...
The production of optically active intermediates and products as pure enantiomers is a topic of ever-increasing importance to the chemical industry. The economic incentives of improved cost...
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