The past three decades have witnessed an explosion of what is now referred to as high-dimensional `omics' data. Bioinformatics Methods: From Omics to Next Generation Sequencing describes the statistical methods and analytic frameworks that are best equipped to interpret these complex data and how they apply to health-related research. Covering the technologies that generate data, subtleties of various data types, and statistical underpinnings of methods, this book identifies a suite of potential analytic tools, and highlights commonalities among statistical methods that have been developed.
An ideal reference for biostatisticians and data analysts that work in collaboration with scientists and clinical investigators looking to ensure rigorous application of available methodologies.
Key Features:
Survey of a variety of omics data types and their unique features
Summary of statistical underpinnings for widely used omics data analysis methods
Description of software resources for performing omics data analyses
The past three decades have witnessed an explosion of what is now referred to as high-dimensional `omics' data. Bioinformatics Methods: From Omics to Next Generation Sequencing describes the statistical methods and analytic frameworks that are best equipped to interpret these complex data and how they apply to health-related research. Covering the technologies that generate data, subtleties of various data types, and statistical underpinnings of methods, this book identifies a suite of potential analytic tools, and highlights commonalities among statistical methods that have been developed.
An ideal reference for biostatisticians and data analysts that work in collaboration with scientists and clinical investigators looking to ensure rigorous application of available methodologies.
Key Features:
Survey of a variety of omics data types and their unique features
Summary of statistical underpinnings for widely used omics data analysis methods
Description of software resources for performing omics data analyses
Section I: Algorithms for interpreting MS and MS/MS dataIntroduction: Assigning peptides and proteins to MS spectraItziar Frades, Ewa Gubb and Rune MatthiesenIdentification of Post-translational...
The three-dimensional structure and function of molecules present many challenges and opportunities for developing an understanding of biological systems. With the increasing availability of...
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