Bioinformatics and Computational Biology

This volume presents the proceedings of the First International Conference on Bioinformatics and Computational Biology (BICoB 2009). This conference was supported by the International Society for Computers and Applications (ISCA) and Springer. Computational techniques have already enabled unprecedented advances in modern biology and medicine. This continues to be a vibrant research area with broadening of computational techniques and new emerging challenges. The Bioinformatics and Computational Biology (BICoB) conference has the goal of promoting the advancement of computing techniques and their application to life sciences. The topics of interest include (and are not limited to): - Genome analysis: genome assembly; genome and chromosome annotation, gene ?nding; alternative splicing; EST analysis and comparative genomics - Sequence analysis: multiple sequence alignment; sequence search and cl- tering; function prediction, motif discovery, functional site recognition in protein, RNA and DNA sequences - Phylogenetics: phylogeny estimation; models of evolution; comparative b- logical methods; population genetics - StructuralBioinformatics:structurematching,prediction,analysisandc- parison; methods and tools for docking; protein design - Analysis of high-throughput biological data: microarrays (nucleic acid, p- tein, array CGH, genome tiling, and other arrays); EST; SAGE; MPSS; proteomics; mass spectrometry - Geneticsandpopulationanalysis:linkageanalysis;associationanalysis;p- ulation simulation; haplotyping; marker discovery; genotype calling - Systems biology: systems approaches to molecular biology; multiscale m- eling; pathways; gene networks BICoB is interested in all areas of computing with an impact on life sciences including (but not limited to) algorithms, databases, languages, systems, and high-performance computing.