Pre-clinical medicine Books

This book is the first overview on Deep Learning (DL) for biomedical data analysis. It surveys the most recent techniques and approaches in this field, with both a broad coverage and enough depth to be of practical use to working professionals. This book...

This volume is dedicated to multidisciplinary research at the interface between basic biomedicine and clinical practice. This book guides best practice in the diagnosis and therapy while dealing with difficult-to-treat disorders of yet unclear...

X-ray imaging is a corner stone of breast cancer diagnosis. By exploiting the phase shift of X-rays rather than their attenuation, phase-contrast tomography has the potential to dramatically increase the visibility of small and low contrast features,...

This book provides a practical guide in the use of imaging and visualization technologies in urology. It details how output from diagnostic systems, can be represented through synthetic, virtual and augmented reality tools, such as holograms and three...

This book provides an introduction to next generation smart screening technology for medical image analysis that combines artificial intelligence (AI) techniques with digital screening to develop innovative methods for detecting breast cancer. The...

This book covers different omics aspects related to the extracellular matrix (ECM), namely specific omics resources focused on the extracellular matrix (e.g., databases, repositories and atlases), quantitative proteomics applied to specific extracellular...

This book provides detailed information on functional anatomy, physical examination, and clinical radiology of the knee with a view to enabling the clinician to identify the most suitable treatment approach to different knee joint pathologies. In...

This book provides a comprehensive overview of the use of PET and SPECT in the classic psychiatric disorders such as depression, bipolar disorder, anxiety disorders, and schizophrenia. In addition, it discusses the application of these functional...

This superbly illustrated atlas serves as a basic introduction to contrast-enhanced mammography (CEM), a breakthrough functional breast imaging modality, which is rapidly growing. This book is an essential guide for the latest...

This book explores how daily and seasonal rhythmicity is generated, how these rhythms are synchronised by our environment, and how they regulate the neuroendocrine systems that impact our physiology and behaviour.The constraints of surviving in a...

This book discusses the unique ion channels and transporters found within the epithelial tissues of various organs, including the kidney, intestine, pancreas and respiratory tract. Authors focus on demonstrating the crucial roles that each of these...

Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of...

This book highlights the latest research on practical applications of computational biology and bioinformatics, and addresses emerging experimental and sequencing techniques that are posing new challenges for bioinformatics and computational biology...

This book discusses unique ion channels and transporters that are located within epithelial tissues of various organs including the kidney, intestine, pancreas and respiratory tract. As the authors show, these channels and transporters play crucial roles...

This book brings together the most up-to-date information about the physiology of progestogens. Addressing the bidirectional communication between hormones, fertility, tumors, and autoimmunity, it provides the basic science and clinical perspectives of...

This book combines the reference material of a nephrology textbook with the everyday relevance of a clinical handbook. This second edition develops and expands upon the success of the first. All the content has been updated and entirely new chapters on...

Drosophila melanogaster (fruit fly) is a highly versatile model with a genetic legacy of more than a century. It provides powerful genetic, cellular, biochemical and molecular biology tools to address many questions extending from basic biology to human...

This book presents a collection of chapters, which address various contexts and challenges of the idea of human enhancement for the purposes of human space missions. The authors discuss pros and cons of mostly biological enhancement of human astronauts...

This book presents the main cardiac pathologies, providing a helpful guide featuring clinical cases and electronic supplementary material.  There are several systematic books on cardiac magnetic resonance, which approach the different pathologies...

This is a reference handbook for young researchers exploring gene and cell therapy. Gene therapy could be defined as a set of strategies modifying gene expression or correcting mutant/defective genes through the administration of DNA (or RNA) to cells,...

This book provides a comprehensive, organized, and concise overview of xenobiotic metabolic enzymes and their health implications. The subjects addressed are broad in scope with an emphasis on recent advances in research on biochemical and biomedical...

This book addresses hot issues in the research and management of difficult-to-treat medical disorders that are commonly encountered, but for which the underlying mechanisms are often unknown.These include the adverse effects of hemodialysis and its...

In this book, experts in the field discuss the latest research in developmental neuroendocrinology. Given that the hypothalamus is the center of neuroendocrine activity, the reader will learn about the molecular specification of hypothalamic cells,...

This easy-to-follow textbook presents an engaging introduction to the fascinating world of medical image analysis. Avoiding an overly mathematical treatment, the text focuses on intuitive explanations, illustrating the key algorithms and concepts in a...

Hormonal influences, both natural and iatrogenic, are implicated in the most frequent health issues of women.  Endometrial cancer is now the most common gynecologic cancer in the United States and the industrialized world. This cancer is strongly...

Saliva as a unique sample for health assessment is gaining attention among researchers of different fields in the last 20 years; being reflected in an impressive increase in the number of papers published studying saliva from different biological aspects...

Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of...

This textbook, intended for advanced undergraduate and graduate students, is an introduction to the physical and mathematical principles used in clinical medical imaging. The first two chapters introduce basic concepts and useful terms used in medical...

This book provides a comprehensive overview of the field of developmental programming of ageing phenotypes. Although gerontological research has traditionally focused on later stages of the life cycle, growing evidence indicates that both the rate of...

This book features 21 papers spanning many different sub-fields in bioinformatics and computational biology, presenting the latest research on the practical applications to promote fruitful interactions between young researchers in different areas...

How do electrical activity and calcium signals in neurons influence the secretion of peptide hormones? This volume presents the current state of knowledge regarding the electrical, calcium signaling and synaptic properties of neuroendocrine systems from...

There are several types of damage that can be found in the male gamete. This book covers the genetic damage in spermatozoa that can originate during spermatogenesis, or during transit in both male and female genital tracts. Damage can also be due to...

This book presents original articles that report on new approaches and developments involving pulmonary disorders. Pulmonary health attracts public concern as lungs are the first line of defense of the organism against various contagions and are directly...

Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of...

This book describes novel algorithms based on interval-valued fuzzy methods that are expected to improve classification and decision-making processes under incomplete or imprecise information. At first, it introduces interval-valued fuzzy sets. It then...

This book is a comprehensive guide to dentomaxillofacial imaging in paediatric dentistry and is an excellent resource for both general dental practitioners and paediatric dentists.  Radiation protection, radiation doses and potential risks of...

Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of...

These chapters analyze texts from Isaac Newton's work to shed new light on scientific understanding at his time. Newton used the concept of "sensorium" in writings intended for a public audience, in relation to both humans and God, but even today there...

¿Busca una manera fácil, divertida y eficiente para desmitificar las estructuras del caballo?Colorear la fisiología equina y sus estructuras es una de las maneras más eficientes para estudiar la estructura y funciones de la Anatomía del caballo. ¡Puede...

Homing Endonucleases: Methods and Protocols aims at providing molecular biologists with a comprehensive resource to identify and characterize homing endonucleases from genomic sequence, to deduce the biological basis of binding...

In this book internationally recognized investigators describe cutting-edge laboratory techniques for the study of Production and In Vivo Applications of Gene Transfer Vectors and Design and Characterization of Gene Transfer Vectors. Readers will find a...

The use of molecular biology and biochemistry to study the regulation of gene expression has become a major feature of research in the biological sciences. Many excellent books and reviews exist that examine the experimental methodology employed in...

Many fundamental discoveries concerning epigenetics and the elucidation of mechanisms of epigenetic regulation have developed from studies performed in plants. In Plant Epigenetics and Epigenomics: Methods and Protocols, leading scientists in the...

In Therapeutic Applications of Ribozymes and Riboswitches: Methods and Protocols, expert researchers in the field provide a complete overview of protocols used in the development of RNA molecule as drugs and drug target. These include methods and...

Bioluminescent Imaging: Methods and Protocols distills a wide range of techniques that use bioluminescence imaging as a tool for visualizing and tracking various biological processes. Covering diverse fields such as cellular and molecular biology,...

In Functional Analysis of DNA and Chromatin, expert researchers in the field provide an overview of standard and more recent methods for the functional analysis of the genetic material. These include methods on DNA-dye binding modes, chromatin staining,...

In miRNA Maturation: Methods and Protocols, expert researchers in the field detail many of the methods which are now commonly used to study miRNA maturation. These included established methods such as fluorescent and non-fluorescent methods for...

PIWI-interacting RNAs (piRNAs) are the third and most-recently discovered group of silencing-inducible small RNAs in animals. PIWI-Interacting RNAs: Methods and Protocols provides the most recent methods and protocols for studying piRNAs in the gonads of...