Pharmacology Books

Authored by renowned leaders in the field, this comprehensive volume covers all aspects of drug-drug interactions, including preclinical, clinical, toxicological, and regulatory perspectives.Thoroughly updated, this second edition reflects the...

This Second Edition is an essential guide to preparing for FDA pre-approval inspections-taking into account current trends in FDA expectations and inspection activities, such as the GMPs of the 21st Century, quality systems-based approach to inspections,...

Responding to the explosion of advances in the use of biomarkers to efficiently, rapidly, and economically evaluate the health effects of chemical entities, this authoritative reference provides a detailed overview of the theory, development, and...

Toxicokinetics in Risk Assessment discusses the noncancer risk assessment process and its reliance on uncertainty factors in order to facilitate the continued study and refinement of the scientific basis for health risk assessment. This text clearly...

The second edition of this text assembles significant ophthalmic advances and encompasses breakthroughs in gene therapy, ocular microdialysis, vitreous drug disposition modelling, and receptor/transporter targeted drug delivery.

Thoroughly revised and updates, this new edition of Ophthalmic Toxicology retains its uniqueness in covering all aspects of ophthalmic toxicology. With chapters from leading authorities incorporating the latest developments in the field, including a new...

The Nobel Prize is the highest award in science, as is the case with nonscience fields too, and it is, therefore, arguably the most internationally recognized award in the world. This unique set of volumes focuses on summarizing the Nobel Prize within...

Brainstorming Questions in Toxicology is designed to serve as a comprehensive, quick reference supplement for various examinations that include sections on toxicology. It reflects the breadth and multidisciplinary nature of toxicology with an...

"Offers a comprehensive, unified presentation of statistical designs and methods of analysis for all stages of pharmaceutical development--emphasizing biopharmaceutical applications and demonstrating statistical techniques with real-world examples."

This book reviews the history, regulatory status, pharmacopeial specifications, and harmonization of pharmaceutical excipients in the United States and Europe, and provides a comprehensive understanding of the current scientific basis for safety...

It is estimated that 80 to 90% of drugs under development never make it to the marketplace due to insufficient clinical activity, unacceptable toxicity, rapid appearance of drug resistance, or other factors that should be, at least partially, predictable...

When a pharmaceutical company decides to build a Quality System, it has to face the fact that there aren't any guideline that define exactly how such a system has to be built. With terms such as quality system, quality assurance, and quality management...

Not since this author's bestselling Manual of Pharmacologic Calculation-long out of print-has there been a reference available for drug data analysis, and even that work did not deal with drug combinations. Although pharmacologists and most other...

Interactions between drug particulates are crucial in determining drug dispersion and deaggregation, and ultimately delivery efficiency. This book combines principles established in surface and colloidal chemistry with pharmaceutical powder technology...

Emphasizing the role of good statistical practices (GSP) in drug research and formulation, this book outlines important statistics applications for each stage of pharmaceutical development to ensure the valid design, analysis, and assessment of drug...

Providing more than just a comprehensive history, critical vocabulary, insightful compilation of motivations, and clear explanation of the state-of-the-art of modern clinical trial simulation, this book supplies a rigorous framework for employing...

Analyzes various reproductive and gynecological disorders encountered in the care of women who do not wish to conceive, as well as those who have difficulty with conception, early pregnancy, and menopause. Discusses the latest strategies in the treatment...

From the laboratory to full-scale commercial production, this reference provides a clear and in-depth analysis of bioreactor design and operation and encompasses critical aspects of the biocatalytic manufacturing process. It clarifies principles in...

This authoritative reference presents an up-to-date review of the testing methods, emerging technologies, and analytical systems and procedures used to prevent the microbial contamination of pharmaceutical processes, products, and environments. It...

Covering regulatory requirements stipulated by the FDA, this book delineates the organization, planning, verification, and documentation activities and procedural controls required for compliance with worldwide computer systems validation regulations...

Knowing how to deal with the regulatory issues, understanding the impacts of cleanliness, and recognizing the affect that poor facility layout will have on GMP spaces are only some of the issues an experienced Project Manager must focus on. Completely...

Providing the guidance needed for formulation, handling, and quality control of photolabile drugs, Photostability of Drugs and Drug Formulations, Second Edition explores the significance of new information on drug photoreactivity in a pharmaceutical...

This second volume of Reviews in Food and Nutrition Toxicity follows on directly from the successes of the first volume published last year. This series disseminates important data pertaining to food and nutrition safety and toxicology that is relevant...

Biopharmaceuticals, the term for genetically engineered therapeutic proteins, monoclonal antibodies, and nucleic acid-based products, have become an increasing part of the pharmaceutical armament. While this category of drugs accounts for approximately...

Investigative Immunotoxicology provides a critical evaluation of proposed experimental animal models and approaches, and discusses the contribution that immunotoxicity can make to the overall assessment of chemical-induced adverse health effects on...

A well-understood tenet exists among the FDA and other regulatory bodies: if you didn't write it down, it didn't happen. And if it didn't happen, your company stands to lose time, money, and perhaps its competitive edge. Write it Down: Guidance for...

Identifying current tools, techniques, and approaches for the evaluation of laboratory operations, this reference reviews the latest regulatory standards and auditing practices to test laboratory safety, quality, and performance.

Addressing issues at the forefront of interest for the Clinical Trial Materials Professional (CTMP), this Second Edition highlights the most critical concepts related to the planning, manufacturing, packaging, labeling, distribution, reconciliation, and...

Gathering information of critical importance for professionals in the pharmaceutical and medical device industries, this guide provides a comprehensive overview of key resources, such as databases, on-line directories, reports, and periodicals-providing...

Divided into three expansive sections on biotechnological advances, applications, and research prospects, this reference provides expert summaries of the state-of-the-science in personal care product development-clearly depicting the latest breakthroughs...

Purposefully designed as a resource for practicing and student toxicologists, Statistics and Experimental Design for Toxicologists and Pharmacologists, Fourth Edition equips you for the regular statistical analysis of experimental data. Starting with the...

All too often, the words "computer validation" strike terror into the hearts of those new to the process and may even cause those familiar with it to tremble. Validating Pharmaceutical Systems: Good Computer Practice in Life Science Manufacturing...

Since the first Handbook of Cell-Penetrating Peptides was prepared in 2001, the wealth of new information on the use of these peptides as transport systems has in fact served to confound the field. The constant internal change in the field of...

Focused extensively on the toxic effect of chemicals on the cardiovascular system, Cardiovascular Toxicology, Fourth Edition is comprised of several key sections beyond cardio and vascular toxicity, such as principles of myocardial cell injury and key...

Being that pharmacokinetics (PK) is the study of how the body handles various substances, it is not surprising that PK plays an important role in the early development of new drugs. However, the clinical research community widely believes that...

The SPSS Survival Manual throws a lifeline to students and researchers grappling with this powerful data analysis software.In her bestselling guide, Julie Pallant takes you through the entire research process, helping you choose the right data analysis...

This book is related to a study involving development and in vitro evaluation of sustained release pellets of ambroxol hydrochloride prepared by extrusion spheronization followed by fluid bed coating with the commercial aqueous polyvinyl acetate...

Simvastatin, a crystalline substance, is a widely used drug for the treatment of hypercholesterolemia. It is a BCS class II drug, having low aqueous solubility (0.76 mg/L) exhibiting poor dissolution pattern and low oral bioavailability (5%). The purpose...

A simple, fast and precise (RP-HPLC) reversed phase high performance liquid chromatographic method is developed for the determination of Nitazoxanide. The linearity of Nitazoxanide was found in the range of 50 to 150 μg/ml. The recovery was calculated by...

In 2020, the spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 virus) led to the worst worldwide healthcare crisis of this century. Several publications regarding the pathogenesis and etiology of SARS-CoV-2 virus have enahnced our...

Psoriasis with psoriatic arthritis is a chronic and difficult-to-treat inflammatory skin condition. Recent developments in biology, immunology, and molecular biology have enabled us to use various targeted therapeutics in treating these conditions, such...

This reprint, entitled "Cardiopulmonary Resuscitation: Clinical Updates and Perspectives", encompasses significant advancements in CPR, reflecting its critical role in emergency care. This Special Issue consolidates thirteen meticulously selected papers,...

The Special Issue features original research articles and review articles that discuss new therapy tactics and target medications, emphasizing the significance of brain tumors at the cellular and molecular levels. In recent decades, potent...

The always-evolving field of pediatric spine surgery has seen tremendous advancements in recent years. Improvements in surgical planning, techniques, implants, and peri-operative pathways have greatly benefited our patients and their families...

To date, numerous research groups have focused on the study and characterization of herbal extracts to identify numerous plant metabolites that have remarkable effects on biological systems.

This Special Issue begins with two preclinical studies on bergamot fruit extract (Citrus bergamia) showing reductions in oxidative stress and dyslipidemia both in vitro and in vivo. Additionally, a review explores the potential therapeutic use of...

The objective of this reprint is to offer readers the most up-to-date insights into managing both ruptured and unruptured cerebral aneurysms. Despite recent advancements in diagnosing and treating these aneurysms, their associated complications...

This Special Issue of Biomedicines, "Role of NO in Disease: Good, Bad or Ugly", focuses on the roles of nitric oxide (NO) in disease from various aspects. NO plays an important role in several physiological processes with numerous biological targets,...